Biofilms: Survival and defense strategy for pathogens

A Kumar, A Alam, M Rani, NZ Ehtesham… - International Journal of …, 2017 - Elsevier
Studies on biofilm related infections are gaining prominence owing to their involvement in
majority of clinical infections. Biofilm, considered as a generic mechanism for survival used …

A mathematical model of quorum sensing induced biofilm detachment

BO Emerenini, BA Hense, C Kuttler, HJ Eberl - PloS one, 2015 - journals.plos.org
Background Cell dispersal (or detachment) is part of the developmental cycle of microbial
biofilms. It can be externally or internally induced, and manifests itself in discrete sloughing …

Three faces of biofilms: a microbial lifestyle, a nascent multicellular organism, and an incubator for diversity

A Penesyan, IT Paulsen, S Kjelleberg… - npj Biofilms and …, 2021 - nature.com
Biofilms are organised heterogeneous assemblages of microbial cells that are encased
within a self-produced matrix. Current estimates suggest that up to 80% of bacterial and …

Novel treatment strategies for biofilm-based infections

C Vuotto, G Donelli - Drugs, 2019 - Springer
Biofilm-growing cells show an enhanced antimicrobial tolerance with respect to the same
cells growing in a free-floating way. This is due to physical or chemical diffusion barriers and …

Combating biofilms

L Yang, Y Liu, H Wu, Z Song, N Høiby… - FEMS Immunology & …, 2012 - academic.oup.com
Biofilms are complex microbial communities consisting of microcolonies embedded in a
matrix of self-produced polymer substances. Biofilm cells show much greater resistance to …

Beneficial applications of biofilms

LA Philipp, K Bühler, R Ulber, J Gescher - Nature Reviews Microbiology, 2023 - nature.com
Many microorganisms live in the form of a biofilm. Although they are feared in the medical
sector, biofilms that are composed of non-pathogenic organisms can be highly beneficial in …

Microbial biofouling: unsolved problems, insufficient approaches, and possible solutions

HC Flemming - Biofilm highlights, 2011 - Springer
Microbial biofouling is a very costly problem, keeping busy a billion dollar industry providing
biocides, cleaners, and antifouling materials worldwide. Basically, five general reasons can …

The biofilm life cycle: expanding the conceptual model of biofilm formation

K Sauer, P Stoodley, DM Goeres… - Nature Reviews …, 2022 - nature.com
Bacterial biofilms are often defined as communities of surface-attached bacteria and are
typically depicted with a classic mushroom-shaped structure characteristic of Pseudomonas …

Engineering biofilm formation and dispersal

TK Wood, SH Hong, Q Ma - Trends in biotechnology, 2011 - cell.com
Anywhere water is in the liquid state, bacteria will exist as biofilms, which are complex
communities of cells that are cemented together. Although frequently associated with …

Biofilms: A new understanding of these microbial communities is driving a revolution that may transform the science of microbiology

JJ Harrison, RJ Turner, LLR Marques, H Ceri - American Scientist, 2005 - JSTOR
with single-celled organisms swim ming about. We might envision these solitary entities
getting together with some of their brethren now and then to cause some disease or spoil …