From short peptides to nanofibers to macromolecular assemblies in biomedicine

Y Loo, S Zhang, CAE Hauser - Biotechnology advances, 2012 - Elsevier
In the last few years, a variety of self-assembling short peptides that consist exclusively of
simple amino acids have been designed and modified. These peptides exhibit self …

Self‐assembling peptides: From a discovery in a yeast protein to diverse uses and beyond

S Zhang - Protein Science, 2020 - Wiley Online Library
Well‐defined nanofiber scaffold hydrogels made of self‐assembling peptides have found
their way into various 3D tissue culture and clinical products. I reflect initial puzzlement of the …

[HTML][HTML] Rational molecular design of complementary self-assembling peptide hydrogels

S Kyle, SH Felton, MJ McPherson… - Advanced healthcare …, 2012 - ncbi.nlm.nih.gov
Over the past 20 years self-assembling peptides have been shown to be of value as
scaffolds in the field of tissue engineering.[1] Self-assembling peptides offer many …

[HTML][HTML] Designer self-assembling peptide nanofiber biological materials

CAE Hauser, S Zhang - Chemical Society Reviews, 2010 - pubs.rsc.org
Scientists and bioengineers have dreamed of designing materials from the bottom up with
the finest detail and ultimate control at the single molecular level. The discovery of a class of …

Self‐assembling peptide nanofiber hydrogels in tissue engineering and regenerative medicine: progress, design guidelines, and applications

S Koutsopoulos - … of Biomedical Materials Research Part A, 2016 - Wiley Online Library
Until the mid‐1980s, mainly biologists were conducting peptide research. This changed with
discoveries that opened new paths of research involving the use of peptides in …

[HTML][HTML] Self-assembly of peptides to nanostructures

D Mandal, AN Shirazi, K Parang - Organic & biomolecular chemistry, 2014 - pubs.rsc.org
The formation of well-ordered nanostructures through self-assembly of diverse organic and
inorganic building blocks has drawn much attention owing to their potential applications in …

Stimuli-responsive, pentapeptide, nanofiber hydrogel for tissue engineering

JD Tang, C Mura, KJ Lampe - Journal of the American Chemical …, 2019 - ACS Publications
Short peptides are uniquely versatile building blocks for self-assembly. Supramolecular
peptide assemblies can be used to construct functional hydrogel biomaterials—an attractive …

Ultrasmall natural peptides self-assemble to strong temperature-resistant helical fibers in scaffolds suitable for tissue engineering

A Mishra, Y Loo, R Deng, YJ Chuah, HT Hee, JY Ying… - Nano Today, 2011 - Elsevier
A new class of systematically designed ultrasmall (tri-to heptamer) peptides presents the
smallest natural, non-aromatic structures that self-assemble in water to hydrogels. The …

[HTML][HTML] Self-assembling peptides: From design to biomedical applications

S La Manna, C Di Natale, V Onesto… - International journal of …, 2021 - mdpi.com
Self-assembling peptides could be considered a novel class of agents able to harvest an
array of micro/nanostructures that are highly attractive in the biomedical field. By modifying …

Nanoscale assembly of functional peptides with divergent programming elements

AM Garcia, M Melchionna, O Bellotto, S Kralj… - ACS …, 2021 - ACS Publications
Self-assembling peptides are being applied both in the biomedical area and as building
blocks in nanotechnology. Their applications are closely linked to their modes of self …