Biomimetic self-assembling peptides as scaffolds for soft tissue engineering

S Maude, E Ingham, A Aggeli - Nanomedicine, 2013 - Taylor & Francis
Tissue engineered therapies are emerging as solutions to several of the medical challenges
facing aging societies. To this end, a fundamental research goal is the development of novel …

Engineering β-sheet peptide assemblies for biomedical applications

Z Yu, Z Cai, Q Chen, M Liu, L Ye, J Ren, W Liao… - Biomaterials …, 2016 - pubs.rsc.org
Hydrogels have been widely studied in various biomedical applications, such as tissue
engineering, cell culture, immunotherapy and vaccines, and drug delivery. Peptide-based …

[HTML][HTML] Novel Materials From the Supramolecular Self-Assembly of Short Helical β3-Peptide Foldamers

K Kulkarni, N Habila, MP Del Borgo… - Frontiers in Chemistry, 2019 - frontiersin.org
Self-assembly is the spontaneous organization of small components into higher-order
structures facilitated by the collective balance of non-covalent interactions. Peptide-based …

Self-assembling multidomain peptide fibers with aromatic cores

EL Bakota, O Sensoy, B Ozgur, M Sayar… - …, 2013 - ACS Publications
Self-assembling multidomain peptides have been shown to have desirable properties, such
as the ability to form hydrogels that rapidly recover following shear-thinning and the potential …

Self-assembling multidomain peptide nanofibers for delivery of bioactive molecules and tissue regeneration

AN Moore, JD Hartgerink - Accounts of chemical research, 2017 - ACS Publications
Conspectus Multidomain peptides (MDPs) are a class of self-assembling peptides that are
organized in a β-sheet motif, resulting in a nanofibrous architecture. This structure is …

Local delivery of proteins and the use of self-assembling peptides

VFM Segers, RT Lee - Drug discovery today, 2007 - Elsevier
Self-assembling peptides are members of a new class of molecules designed for tissue
engineering and protein delivery. Upon injection in a physiological environment, self …

Hierarchical Self‐Assembly of Peptides and its Applications in Bionanotechnology

BB Gerbelli, SV Vassiliades, JEU Rojas… - Macromolecular …, 2019 - Wiley Online Library
Self‐assembled structures obtained from organic molecules have shown great potential for
applications in a wide range of domains. In this context, short peptides prove to be a …

Self-assembling peptide nanofibrous hydrogel as a versatile drug delivery platform

Z Yu, Q Xu, C Dong, SS Lee, L Gao, Y Li… - Current …, 2015 - ingentaconnect.com
Molecular hydrogels have been widely explored in various biomedical applications, such as
cell culture, tissue engineering and drug delivery. Peptide-based hydrogel nanoparticles …

Self-assembly of short peptides to form hydrogels: Design of building blocks, physical properties and technological applications

G Fichman, E Gazit - Acta biomaterialia, 2014 - Elsevier
Hydrogels are unique supramolecular solid-like assemblies composed mainly of water
molecules that are held by molecular networks. Physical hydrogels that are formed by a set …

Stimuli-responsive self-assembling peptides made from antibacterial peptides

Y Liu, Y Yang, C Wang, X Zhao - Nanoscale, 2013 - pubs.rsc.org
How to use bioactive peptide sequences as fundamental building blocks to make hydrogel
materials which are stimuli-responsive? In this article, we provide a novel designed peptide …