The 2017 Surviving Sepsis Campaign guidelines endorse a focus on the rapidity of
treatment once sepsis has been identified, with a strong recommendation for the …

Objectives: To assess the mortality benefits of timely antibiotic treatment of adults present at
the emergency department with sepsis and compare one-hour administration and 3-hour …

This study aims to determine the impact of prompt administration of antibiotics in evaluating
the prognosis of patients with septic shock or sepsis. On January 1, 2022, we searched the …

Objectives: We sought to systematically review and meta-analyze the available data on the
association between timing of antibiotic administration and mortality in severe sepsis and …

Objectives To evaluate the effect of timing and appropriateness of antibiotics administration
on mortality in patients diagnosed with sepsis according to the Sepsis-3 definition. Methods …

Objectives To review the impact of the timeliness of antibiotic therapy on the outcome of
patients with sepsis or septic shock. Methods We searched MEDLINE, EMBASE, the …

Purpose The goal of this review was to synthesize existing evidence regarding outcomes
(mortality) for patients who present to the emergency department, are administered …

Study objective Debate exists about the mortality benefit of administering antibiotics within
either 1 or 3 hours of sepsis onset. We performed this meta-analysis to analyze the effect of …

Background The use of antibiotics is essential in the treatment of sepsis and septic shock,
and delaying their administration may impact patient mortality outcomes. However, there is …

Background The Surviving Sepsis Campaign recommends the administration of antibiotics
within 1 hour of triage time in sepsis patients. The purpose of this study was to determine the …