Epigenome‐wide study identifies novel methylation loci associated with body mass index and waist circumference
Objective To conduct an epigenome‐wide analysis of DNA methylation and obesity traits.
Methods DNA methylation was quantified in CD4+ T‐cells using the Illumina Infinium …
Methods DNA methylation was quantified in CD4+ T‐cells using the Illumina Infinium …
DNA methylation and obesity traits: An epigenome-wide association study. The REGICOR study
S Sayols-Baixeras, I Subirana, A Fernández-Sanlés… - Epigenetics, 2017 - Taylor & Francis
Obesity is associated with increased risk of several diseases and has become epidemic.
Obesity is highly heritable but the genetic variants identified by genome-wide association …
Obesity is highly heritable but the genetic variants identified by genome-wide association …
[HTML][HTML] A genome-wide mQTL analysis in human adipose tissue identifies genetic variants associated with DNA methylation, gene expression and metabolic traits
P Volkov, AH Olsson, L Gillberg, SW Jørgensen… - PloS one, 2016 - journals.plos.org
Little is known about the extent to which interactions between genetics and epigenetics may
affect the risk of complex metabolic diseases and/or their intermediary phenotypes. We …
affect the risk of complex metabolic diseases and/or their intermediary phenotypes. We …
Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci
EW Demerath, W Guan, ML Grove… - Human molecular …, 2015 - academic.oup.com
Obesity is an important component of the pathophysiology of chronic diseases. Identifying
epigenetic modifications associated with elevated adiposity, including DNA methylation …
epigenetic modifications associated with elevated adiposity, including DNA methylation …
Epigenome-wide association in adipose tissue from the METSIM cohort
Most epigenome-wide association studies to date have been conducted in blood. However,
metabolic syndrome is mediated by a dysregulation of adiposity and therefore it is critical to …
metabolic syndrome is mediated by a dysregulation of adiposity and therefore it is critical to …
Epigenome-wide association study of fasting blood lipids in the genetics of lipid-lowering drugs and diet network study
Background—Genetic research regarding blood lipids has largely focused on DNA
sequence variation; few studies have explored epigenetic effects. Genome-wide surveys of …
sequence variation; few studies have explored epigenetic effects. Genome-wide surveys of …
[HTML][HTML] Impact of BMI and waist circumference on epigenome-wide DNA methylation and identification of epigenetic biomarkers in blood: an EWAS in multi-ethnic …
Background The prevalence of obesity and its related chronic diseases have been
increasing especially in Asian countries. Obesity-related genetic variants have been …
increasing especially in Asian countries. Obesity-related genetic variants have been …
[HTML][HTML] An analysis of DNA methylation in human adipose tissue reveals differential modification of obesity genes before and after gastric bypass and weight loss
Background Environmental factors can influence obesity by epigenetic mechanisms.
Adipose tissue plays a key role in obesity-related metabolic dysfunction, and gastric bypass …
Adipose tissue plays a key role in obesity-related metabolic dysfunction, and gastric bypass …
[HTML][HTML] Genetic effects on DNA methylation and its potential relevance for obesity in Mexican Americans
Several studies have identified effects of genetic variation on DNA methylation patterns and
associated heritability, with research primarily focused on Caucasian individuals. In this …
associated heritability, with research primarily focused on Caucasian individuals. In this …
Genome-wide methylation analysis identifies differentially methylated CpG loci associated with severe obesity in childhood
Childhood obesity is a major public health issue. Here we investigated whether differential
DNA methylation was associated with childhood obesity. We studied DNA methylation …
DNA methylation was associated with childhood obesity. We studied DNA methylation …