Objective To conduct an epigenome‐wide analysis of DNA methylation and obesity traits.
Methods DNA methylation was quantified in CD4+ T‐cells using the Illumina Infinium …

Obesity is associated with increased risk of several diseases and has become epidemic.
Obesity is highly heritable but the genetic variants identified by genome-wide association …

Little is known about the extent to which interactions between genetics and epigenetics may
affect the risk of complex metabolic diseases and/or their intermediary phenotypes. We …

Obesity is an important component of the pathophysiology of chronic diseases. Identifying
epigenetic modifications associated with elevated adiposity, including DNA methylation …

Most epigenome-wide association studies to date have been conducted in blood. However,
metabolic syndrome is mediated by a dysregulation of adiposity and therefore it is critical to …

Background—Genetic research regarding blood lipids has largely focused on DNA
sequence variation; few studies have explored epigenetic effects. Genome-wide surveys of …

Background The prevalence of obesity and its related chronic diseases have been
increasing especially in Asian countries. Obesity-related genetic variants have been …

Background Environmental factors can influence obesity by epigenetic mechanisms.
Adipose tissue plays a key role in obesity-related metabolic dysfunction, and gastric bypass …

Several studies have identified effects of genetic variation on DNA methylation patterns and
associated heritability, with research primarily focused on Caucasian individuals. In this …

Childhood obesity is a major public health issue. Here we investigated whether differential
DNA methylation was associated with childhood obesity. We studied DNA methylation …