The era of gene therapy: From preclinical development to clinical application
Three decades of promise have culminated in the development of gene therapies that can
be applied to a broad range of human diseases. After a brief history, we provide an overview …
be applied to a broad range of human diseases. After a brief history, we provide an overview …
[HTML][HTML] Gene therapy clinical trials, where do we go? An overview
There have been many ups and downs since the introduction of gene therapy as a
therapeutic modality for diseases. However, the journey of gene therapy has reached a …
therapeutic modality for diseases. However, the journey of gene therapy has reached a …
[HTML][HTML] Development and clinical translation of approved gene therapy products for genetic disorders
A Shahryari, M Saghaeian Jazi, S Mohammadi… - Frontiers in …, 2019 - frontiersin.org
The field of gene therapy is striving more than ever to define a path to the clinic and the
market. Twenty gene therapy products have already been approved and over two thousand …
market. Twenty gene therapy products have already been approved and over two thousand …
Entering the modern era of gene therapy
XM Anguela, KA High - Annual review of medicine, 2019 - annualreviews.org
Gene therapies are gaining momentum as promising early successes in clinical studies
accumulate and examples of regulatory approval for licensing increase. Investigators are …
accumulate and examples of regulatory approval for licensing increase. Investigators are …
[HTML][HTML] Gene therapy: an overview of approved and pipeline technologies
A Sinclair, S Islam, S Jones - 2019 - europepmc.org
Gene Therapy: An Overview of Approved and Pipeline Technologies - Abstract - Europe PMC
Sign in | Create an account https://orcid.org Europe PMC Menu About Tools Developers Help …
Sign in | Create an account https://orcid.org Europe PMC Menu About Tools Developers Help …
Clinical translation of gene medicine
F Wang, Z Qin, H Lu, S He, J Luo… - The journal of gene …, 2019 - Wiley Online Library
Gene therapy has recently witnessed accelerated progress as a new therapeutic strategy
with the potential to treat a range of inherited and acquired diseases. Billions of dollars have …
with the potential to treat a range of inherited and acquired diseases. Billions of dollars have …
Gene therapy clinical trials worldwide to 2012–an update
SL Ginn, IE Alexander, ML Edelstein… - The journal of gene …, 2013 - Wiley Online Library
To date, over 1800 gene therapy clinical trials have been completed, are ongoing or have
been approved worldwide. Our database brings together global information on gene therapy …
been approved worldwide. Our database brings together global information on gene therapy …
[HTML][HTML] Clinical development of gene therapies: the first three decades and counting
L Lapteva, T Purohit-Sheth, M Serabian… - … Therapy-Methods & …, 2020 - cell.com
In the past three decades the field of gene therapy has made remarkable progress, surging
from mere laboratory experiments to US Food and Drug Administration (FDA)-approved …
from mere laboratory experiments to US Food and Drug Administration (FDA)-approved …
Gene therapy clinical trials worldwide to 2017: An update
To date, almost 2600 gene therapy clinical trials have been completed, are ongoing or have
been approved worldwide. Our database brings together global information on gene therapy …
been approved worldwide. Our database brings together global information on gene therapy …
Gene therapy: a double-edged sword with great powers
R Tang, Z Xu - Molecular and cellular biochemistry, 2020 - Springer
Gene therapy is the treatment of a disease through transferring genetic material into cells of
the patients. In the recent several years, gene therapy has experienced rapid progress and …
the patients. In the recent several years, gene therapy has experienced rapid progress and …
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