Identification of novel non-homologous drug targets against Acinetobacter baumannii using subtractive genomics and comparative metabolic pathway analysis
Lack of effective antibiotics and the development of multidrug resistance in clinical isolates
of nosocomial pathogen Acinetobacter baumanni has necessitated the identification of novel …
of nosocomial pathogen Acinetobacter baumanni has necessitated the identification of novel …
Identification of putative non-host essential genes and novel drug targets against Acinetobacter baumannii by in silico comparative genome analysis
Acinetobacter baumannii, the gram-negative bacteria emerged as an extremely critical
pathogen causing nosocomial and different kinds of infections. A. baumannii exhibit …
pathogen causing nosocomial and different kinds of infections. A. baumannii exhibit …
[PDF][PDF] In silico identification of novel drug targets in acinetobacter baumannii by subtractive genomic approach
Objective: Multiple drug resistance (MDR) in bacteria, particularly Gram-negative bacilli, has
significantly hindered the treatment of infections caused by these bacteria. This results in the …
significantly hindered the treatment of infections caused by these bacteria. This results in the …
Identification of Druggable Targets for Acinetobacter baumannii Via Subtractive Genomics and Plausible Inhibitors for MurA and MurB
N Kaur, M Khokhar, V Jain, PV Bharatam… - Applied biochemistry …, 2013 - Springer
Emergence of the multidrug-resistant pathogens has rendered the current therapies
ineffective thereby, resulting in the need for new drugs and drug targets. The accumulating …
ineffective thereby, resulting in the need for new drugs and drug targets. The accumulating …
Computer-Based Identification of Potential Druggable Targets in Multidrug-Resistant Acinetobacter baumannii: A Combined In Silico, In Vitro and In Vivo Study
The remarkable rise in antimicrobial resistance is alarming for Acinetobacter baumannii,
which necessitates effective strategies for the discovery of promising anti-acinetobacter …
which necessitates effective strategies for the discovery of promising anti-acinetobacter …
Proteomic Analyses of Acinetobacter baumannii Clinical Isolates to Identify Drug Resistant Mechanism
P Wang, RQ Li, L Wang, WT Yang, QH Zou… - Frontiers in cellular and …, 2021 - frontiersin.org
Acinetobacter baumannii is one of the main causes of nosocomial infections. Increasing
numbers of multidrug-resistant Acinetobacter baumannii cases have been reported in recent …
numbers of multidrug-resistant Acinetobacter baumannii cases have been reported in recent …
In Silico Identification of Probable Drug and Vaccine Candidates Against Antibiotic-Resistant Acinetobacter baumannii
E Zadeh Hosseingholi, G Zarrini… - Microbial Drug …, 2020 - liebertpub.com
Acinetobacter baumannii is known as a Gram-negative bacterium that has become one of
the most important health problems due to antibiotic resistance. Today, numerous efforts are …
the most important health problems due to antibiotic resistance. Today, numerous efforts are …
Screening of potential lead molecules against prioritised targets of multi-drug-resistant-Acinetobacter baumannii – insights from molecular docking, molecular dynamic …
S Skariyachan, M Manjunath… - Journal of Biomolecular …, 2019 - Taylor & Francis
Acinetobacter baumannii, an opportunistic pathogen, has become multi-drug resistant
(MDR) to major classes of antibacterial and poses grave threat to public health. The current …
(MDR) to major classes of antibacterial and poses grave threat to public health. The current …
Genome-Wide Identification of Potential Drug Target in Enterobacteriaceae Family: A Homology-Based Method
M Hadizadeh, SN Tabatabaiepour… - Microbial Drug …, 2018 - liebertpub.com
The Enterobacteriaceae is a large family of Gram-negative, facultative anaerobic, non-spore
forming rod-shaped bacteria that includes harmless and pathogenic organisms. The …
forming rod-shaped bacteria that includes harmless and pathogenic organisms. The …
Identification of a Family of Glycoside Derivatives Biologically Active against Acinetobacter baumannii and Other MDR Bacteria Using a QSPR Model
As the rate of discovery of new antibacterial compounds for multidrug-resistant bacteria is
declining, there is an urge for the search for molecules that could revert this tendency …
declining, there is an urge for the search for molecules that could revert this tendency …
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