Health effects research and regulation of diesel exhaust: an historical overview focused on lung cancer risk

TW Hesterberg, CM Long, WB Bunn, CA Lapin… - Inhalation …, 2012 - Taylor & Francis
The mutagenicity of organic solvent extracts from diesel exhaust particulate (DEP), first
noted more than 55 years ago, initiated an avalanche of diesel exhaust (DE) health effects …

Lung cancer and diesel exhaust: an updated critical review of the occupational epidemiology literature

JF Gamble, MJ Nicolich, P Boffetta - Critical reviews in toxicology, 2012 - Taylor & Francis
A recent review concluded that the evidence from epidemiology studies was indeterminate
and that additional studies were required to support the diesel exhaust-lung cancer …

A critical assessment of studies on the carcinogenic potential of diesel exhaust

TW Hesterberg, WB Bunn III, GR Chase… - Critical reviews in …, 2006 - Taylor & Francis
After decades of research involving numerous epidemiologic studies and extensive
investigations in laboratory animals, a causal relationship between diesel exhaust (DE) …

Lung cancer and diesel exhaust: a critical review of the occupational epidemiology literature

J Gamble - Critical reviews in toxicology, 2010 - Taylor & Francis
The diesel exhaust (DE)–lung cancer hypothesis is evaluated. Diesel power became
common after World War II, exposure was to traditional diesel exhaust (TDE) before 1988. In …

The diesel exhaust in miners study: a cohort mortality study with emphasis on lung cancer

MD Attfield, PL Schleiff, JH Lubin, A Blair… - Journal of the …, 2012 - academic.oup.com
Background Current information points to an association between diesel exhaust exposure
and lung cancer and other mortality outcomes, but uncertainties remain. Methods We …

Lung cancer mortality and diesel exhaust: reanalysis of a retrospective cohort study of US railroad workers

KS Crump - Inhalation toxicology, 1999 - Taylor & Francis
A retrospective cohort study of 55,407 US railroad workers has been called the most
definitive study linking exposure to diesel exhaust (DE) with lung cancer in humans …

Meta-analysis of rat lung tumors from lifetime inhalation of diesel exhaust.

PA Valberg, EA Crouch - Environmental health perspectives, 1999 - ehp.niehs.nih.gov
Estimating the carcinogenic potential of exposure to diesel-engine exhaust particulates
(DEPs) is problematic. In rats, high concentrations of DEPs (> 1,000 microg/m (3)) inhaled …

The diesel exhaust in miners study: a nested case–control study of lung cancer and diesel exhaust

DT Silverman, CM Samanic, JH Lubin… - Journal of the …, 2012 - academic.oup.com
Background Most studies of the association between diesel exhaust exposure and lung
cancer suggest a modest, but consistent, increased risk. However, to our knowledge, no …

Historical estimation of diesel exhaust exposure in a cohort study of US railroad workers and lung cancer

F Laden, JE Hart, A Eschenroeder, TJ Smith… - Cancer Causes & …, 2006 - Springer
We have previously shown an elevated risk of lung cancer mortality in diesel exhaust
exposed railroad workers. To reduce exposure misclassification, we obtained extensive …

Diesel exhaust causes lung cancer: now what?

DT Silverman - Occupational and environmental medicine, 2017 - oem.bmj.com
After three decades of epidemiological research, diesel exhaust was classified as a
carcinogen in humans by the International Agency for Research on Cancer (IARC) in 2012 …