Sulfur dioxide-induced exacerbation of airway inflammation via reactive oxygen species production and the toll-like receptor 4/nuclear factor-κB pathway in asthmatic …

L Zhang, H Yi, N Sang - Toxicology and Industrial Health, 2021 - journals.sagepub.com
Sulfur dioxide (SO2) is a common air pollutant that can exacerbate asthmatic airway
inflammation. The mechanisms underlying these effects are not yet fully understood. In this …

Sulfur dioxide exposure enhances Th2 inflammatory responses via activating STAT6 pathway in asthmatic mice

X Li, L Huang, N Wang, H Yi, H Wang - Toxicology letters, 2018 - Elsevier
Sulfur dioxide (SO 2) is one of potential risk factors for induction and/or exacerbation of
asthma, but the underlying mechanisms are not well understood. In this study, we …

Effect of sulfur dioxide on inflammatory and immune regulation in asthmatic rats

R Li, X Kou, J Tian, Z Meng, Z Cai, F Cheng, C Dong - Chemosphere, 2014 - Elsevier
Background Exposure to sulfur dioxide (SO 2) increases asthma risk. Inflammatory and
immune responses are typical in asthma disease. The exact effect of SO 2 on modulation of …

Chronic exposure to sulfur dioxide enhances airway hyperresponsiveness only in ovalbumin-sensitized rats

A Song, Q Liao, J Li, F Lin, E Liu, X Jiang, L Deng - Toxicology letters, 2012 - Elsevier
Sulfur dioxide (SO2) is a common air pollutant that triggers asthmatic symptoms, but its
toxicological mechanisms are not fully understood. Specifically, it is unclear how airborne …

Effects of sulfur dioxide derivatives on four asthma-related gene expressions in human bronchial epithelial cells

R Li, Z Meng, J Xie - Toxicology letters, 2007 - Elsevier
Sulfur dioxide (SO2) is a common air pollutant, and inhaled SO2 in airway epithelium easily
forms its soluble derivatives in vivo (bisulfite and sulfite), which are toxic to the respiratory …

The spontaneously hypertensive rat: an experimental model of sulfur dioxide–induced airways disease

UP Kodavanti, MC Schladweiler… - Toxicological …, 2006 - academic.oup.com
Chronic obstructive pulmonary disease (COPD) is characterized by airway obstruction,
inflammation, and mucus hypersecretion, features that are common in bronchitis …

Mechanisms of Heightened Airway Sensitivity and Responses to Inhaled SO2 in Asthmatics

AL Reno, EG Brooks… - Environmental health …, 2015 - journals.sagepub.com
Sulfur dioxide (SO2) is a problematic inhalable air pollutant in areas of widespread
industrialization, not only in the United States but also in countries undergoing rapid …

Sulfur dioxide reduces lipopolysaccharide-induced acute lung injury in rats

Y Zhai, XL Huang, HJ Ma, XH Zhou, JL Zhou… - … European Journal of …, 2019 - termedia.pl
Results Six hours after LPS treatment, rats exhibited elevated pulmonary artery hypertension
(PAH), marked pulmonary structure injury with elevated pulmonary myeloperoxidase (MPO) …

Fine particulate matter and sulfur dioxide coexposures induce rat lung pathological injury and inflammatory responses via TLR4/p38/NF-κB pathway

R Li, L Zhao, J Tong, Y Yan… - International journal of …, 2017 - journals.sagepub.com
Fine particulate matter (PM2. 5) and sulfur dioxide (SO2) are 2 common air pollutants, but
their toxicological effects of coexposure are still not fully clear. In this study, SO2 exposure …

Effects of sulfur dioxide on the expressions of EGF, EGFR, and COX-2 in airway of asthmatic rats

R Li, Z Meng, J Xie - Archives of environmental contamination and …, 2008 - Springer
The pathogenesis of asthma involves a combination of genetic and environmental factors.
The epidemiology studies have shown that SO 2 might play an important role in the initiation …