Association between CASR Polymorphisms, Calcium Intake, and Colorectal Cancer Risk
Aim The current study aimed to assess the effect of dietary calcium intake and possible
interactions with calcium-sensing receptor (CASR) gene polymorphisms on colorectal …
interactions with calcium-sensing receptor (CASR) gene polymorphisms on colorectal …
CASR rs1801725 polymorphism is associated with the risk and prognosis of colorectal cancer: A case‐control study
YE Diao, Q Xu - Journal of Clinical Laboratory Analysis, 2020 - Wiley Online Library
Background The extracellular calcium‐sensing receptor (CASR) controls body calcium
homeostasis. Increased levels of calcium are associated with protecting against colorectal …
homeostasis. Increased levels of calcium are associated with protecting against colorectal …
Association of genetic variants in the calcium-sensing receptor with risk of colorectal adenoma
Objective: Evidence suggests that calcium prevents colorectal cancer, possibly mediated
through the calcium-sensing receptor (CASR). We assessed the associations between …
through the calcium-sensing receptor (CASR). We assessed the associations between …
Calcium intake and risk of colorectal cancer according to expression status of calcium-sensing receptor (CASR)
Objective Although evidence suggests an inverse association between calcium intake and
the risk of colorectal cancer, the mechanisms remain unclear. The calcium-sensing receptor …
the risk of colorectal cancer, the mechanisms remain unclear. The calcium-sensing receptor …
Genetic variation in calcium-sensing receptor and risk for colon cancer
Background: Experimental and epidemiologic studies have suggested that high calcium
intake is associated with decreased colon cancer risk, yet very limited data are available for …
intake is associated with decreased colon cancer risk, yet very limited data are available for …
Calcium intake and genetic variants in the calcium sensing receptor in relation to colorectal cancer mortality: an international consortium study of 18,952 patients
E Wesselink, W Gauderman, SI Berndt, H Brenner… - BJC reports, 2024 - nature.com
Background Research on calcium intake as well as variants in the calcium sensor receptor
(CaSR) gene and their interaction in relation to CRC survival is still limited. Methods Data …
(CaSR) gene and their interaction in relation to CRC survival is still limited. Methods Data …
Effects of the lactase 13910 C/T and calcium-sensor receptor A986S G/T gene polymorphisms on the incidence and recurrence of colorectal cancer in Hungarian …
K Bácsi, E Hitre, JP Kósa, H Horváth, Á Lazáry… - BMC cancer, 2008 - Springer
Background Epidemiological studies suggested the chemopreventive role of higher calcium
intake in colorectal carcinogenesis. We examined genetic polymorphisms that might …
intake in colorectal carcinogenesis. We examined genetic polymorphisms that might …
[HTML][HTML] The calcium-sensing receptor: A promising target for prevention of colorectal cancer
A Aggarwal, M Prinz-Wohlgenannt… - … et Biophysica Acta (BBA …, 2015 - Elsevier
The inverse correlation between dietary calcium intake and the risk of colorectal cancer
(CRC) is well known, but poorly understood. Expression of the calcium-sensing receptor …
(CRC) is well known, but poorly understood. Expression of the calcium-sensing receptor …
No Evidence of Gene–Calcium Interactions from Genome-Wide Analysis of Colorectal Cancer Risk
M Du, X Zhang, M Hoffmeister, RE Schoen… - … Biomarkers & Prevention, 2014 - AACR
Background: Calcium intake may reduce risk of colorectal cancer, but the mechanisms
remain unclear. Studies of interaction between calcium intake and SNPs in calcium-related …
remain unclear. Studies of interaction between calcium intake and SNPs in calcium-related …
Parathyroid hormone gene rs6256 and calcium sensing receptor gene rs1801725 variants are not associated with susceptibility to colorectal cancer in Iran
T Mahmoudi, K Karimi, M Arkani… - Asian Pacific Journal …, 2014 - koreascience.kr
Background: Substantial evidence from epidemiological studies has suggested that
increased levels of calcium may play a protective role against colorectal cancer (CRC) …
increased levels of calcium may play a protective role against colorectal cancer (CRC) …
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