Antitumor activity and antitumor mechanism of triphenylphosphonium chitosan against liver carcinoma

H Huang, H Wu, Y Huang, S Zhang… - Journal of Materials …, 2018 - cambridge.org
N-(3-Carboxypropyl) triphenylphosphonium bromide chitosan (TPPB-CS) was synthesized
and characterized by FTIR, 1H NMR spectrometer, and Zeta potential. TPPB-CS showed a …

Novel water soluble phosphonium chitosan derivatives: Synthesis, characterization and cytotoxicity studies

L Wang, X Xu, S Guo, Z Peng, T Tang - International journal of biological …, 2011 - Elsevier
Novel water soluble phosphonium chitosan derivatives (WSPCSs) with two different degrees
of substitution (3.6% and 4.2%) of quaternary phosphonium were synthesized in a …

Anticancer therapeutic potential of phosphorylated galactosylated chitosan against N-nitrosodiethyl amine-induced hepatocarcinogenesis

U Anushree, S Shetty, SD Kulkarni, H Kumar… - Archives of Biochemistry …, 2022 - Elsevier
Chitosan is a natural polyfunctional polymer that can be modified to achieve compounds
with tailored properties for targeting and treating different cancers. In this study, we report the …

Therapeutic role of a synthesized calcium phosphate nanocomposite material on hepatocarcinogenesis in rats

M Mohammed, E Abdel-Gawad… - … and Cell Biology, 2016 - cdnsciencepub.com
Nanotechnology research is booming worldwide, and the general belief is that medical and
biological applications will form the greatest sector of expansion over the next decade. With …

Enhancing anticancer efficacy: xovoltib-loaded chitosan-tripolyphosphate nanoparticles for targeted drug delivery against MCF-7 breast cancer cells

P Rani, H Jenifer, A Prabhu, D David… - Materials …, 2024 - Taylor & Francis
The objective of this study is to obtain precise medication delivery by combining the drug
xovoltib with chitosan nanoparticles that are synthesized from the cuttlebone of sepia. The …

[HTML][HTML] Paclitaxel-loaded trimethyl chitosan-based polymeric nanoparticle for the effective treatment of gastroenteric tumors

RF Song, XJ Li, XL Cheng, AR Fu… - Oncology …, 2014 - spandidos-publications.com
Gastroenteric cancer is one of the most prevalent cancers and is responsible for most cancer-
related deaths worldwide. Paclitaxel (PTX), a classical microtubule inhibitor, is indicated in …

Zwitterionic choline phosphate functionalized chitosan with antibacterial property and superior water solubility

M Lu, S Yu, Z Wang, Q Xin, T Sun, X Chen, Z Liu… - European Polymer …, 2020 - Elsevier
As a biocompatible natural polymer material, chitosan (CS) is widely used in biomedical
fields due to its excellent properties such as antibacterial ability. However, the main …

Preparation, characterization, and cytotoxicity of various chitosan nanoparticles

Q Yao, W Liu, XJ Gou, XQ Guo, J Yan… - Journal of …, 2013 - Wiley Online Library
Chitosan nanoparticles (CS‐NPs) without drug loading have diverse biological activity. In
this study, we prepared CS‐NPs, CS‐NPs solidified by different amount of glutaraldehyde …

In vitro evaluation on novel modified chitosan for targeted antitumor drug delivery

D Qu, H Lin, N Zhang, J Xue, C Zhang - Carbohydrate polymers, 2013 - Elsevier
In this study, a novel amphiphilic copolymer designed as N-octyl-N-phthalyl-3, 6-O-(2-
hydroxypropyl) chitosan (OPHPC) were synthesized and then conjugated with folic acid (FA …

Cytotoxic activities of chitosan nanoparticles and copper-loaded nanoparticles

L Qi, Z Xu, X Jiang, Y Li, M Wang - Bioorganic & medicinal chemistry letters, 2005 - Elsevier
Chitosan nanoparticles and copper (II)-loaded chitosan nanoparticles were prepared based
on the ionic gelation of chitosan with tripolyphosphate anions and copper ion sorption. In …