Background: In order to provide a reliable non-invasive method for fetal sex determination in
a routine setting, we evaluated the possibility of identifying the fetal Y chromosome-specific …

The aim of the study was to demonstrate the influence of target gene and amplification
product length on the performance of fetal gender determination systems using maternal …

Background The passage of nucleated cells between mother and fetus is well recognized
(Lo et al., 1989, 1996). As well as, cell-free fetal DNA in maternal plasma or serum is at …

Two pairs of primers were designed based on the sequence of bovine Sry and applied to the
assay of Sry sequence from maternal blood using the polymerase chain reaction. Of the total …

Purpose: To find the most effective method for extraction of cell-free DNA (cf-DNA) from
maternal plasma, we compared a blood DNA extraction system (blood kit) and a viral DNA …

INTRODUCTION: Non-invasive methods using maternal plasma and serum for molecular
genetic diagnosis become an important field of interest in prenatal genetic diagnosis. Free …

Objective. The aim of this study was to evaluate the specificity and sensitivity of the real-time
quantitative PCR method for fetal gender determination in early pregnancy. Methods. Blood …

The Sry gene is key in determining male testis formation located in the sex-determining
region of the Y chromosome during gonadal differentiation. In the present study, the Sry …

Since the discovery of the presence of fetal DNA in maternal blood, non-invasive fetal sex
determination has been the test most widely translated into clinical practice. To date there is …

An Erratum has been published for this article in Prenatal Diagnosis 22 (13) 2002, 1241.
Fetal sex prediction can be achieved using PCR targeted at the SRY gene by analysing cell …