Purpose: To prospectively validate a protocol for noninvasive fetal sex determination in
maternal plasma and demonstrate its applicability to clinical practice. Methods: Peripheral …

In previous years, identification of fetal cells in maternal blood circulation has caused a new
revolution in non-invasive method of prenatal diagnosis. Low number of fetal cells in …

We have examined the expression of SRY mRNA in individual in vitro fertilized
preimplantation human embryos; because of ethical constraints, these studies were …

Sex determination in mammals is controlled by the Y chromosome located SRY gene.
Despite recent advances tow ards understanding the mechanisms that regulate sex …

Background To review the possible mechanisms proposed to explain the etiology of 46, XX
sex reversal by investigating the clinical characteristics and their relationships with …

The aims of this investigation were (1) to establish an early noninvasive prenatal genetic
diagnosis of fetal sex by analyzing the DYS14 and SRY genes and (2) to determine the fetal …

The sex of an embryo is determined by genetic sex due to presence or absence of Y
chromosome, but it may not be true in all. We hereby report an interesting case of a …

In normal ontogenetic development, the expression of the sex‐determining region of the Y
chromosome (SRY) gene, involved in the first step of male sex differentiation, is …

Aim: A number of studies for the measurement of cell‐free fetal DNA in maternal blood have
been reported; however, their clinical significance has remained unclear. We proposed to …

Objective Aiming to develop more reliable methods for determination of fetal gender from
maternal plasma we compared three different systems of polymerase chain reaction (PCR) …