[HTML][HTML] Genetic and epigenetic alterations in pancreatic neuroendocrine tumors

A Tirosh, E Kebebew - Journal of gastrointestinal oncology, 2020 - ncbi.nlm.nih.gov
Neuroendocrine tumors (NETs) are a heterogenous group of tumors that originate from
neuroendocrine cells, mainly in the pancreas and the gastrointestinal and …

[HTML][HTML] A direct comparison of patients with hereditary and sporadic pancreatic neuroendocrine tumors: evaluation of clinical course, prognostic factors and genotype …

P Soczomski, B Jurecka-Lubieniecka… - Frontiers in …, 2021 - frontiersin.org
Introduction Pancreatic neuroendocrine tumors (PNETs) in hereditary syndromes pose a
significant challenge to clinicians. The rarity of these syndromes and PNETs itself make it …

[HTML][HTML] Insights into Epigenetic Changes Related to Genetic Variants and Cells-of-Origin of Pancreatic Neuroendocrine Tumors: An Algorithm for Practical Workup

OA Ciobanu, SC Martin, V Herlea, S Fica - Cancers, 2022 - mdpi.com
Simple Summary Pancreatic neuroendocrine tumors are composite entities due to their
heterogeneity illustrated in clinical behavior, mutational pattern, and site of origin. Pancreatic …

Genetics of pancreatic neuroendocrine tumors

C Mohindroo, F McAllister… - Hematology …, 2022 - hemonc.theclinics.com
Pancreatic neuroendocrine tumors (pNETs) are characterized as a rare disease with an
incidence of less than 1 in 100,000 individuals per year, and accounts for 1% to 2% of all …

Molecular profiling of pancreatic neuroendocrine tumors (pNETS) and the clinical potential

M Camilli, K Papadimitriou, A Nogueira… - Expert review of …, 2018 - Taylor & Francis
Introduction: Pancreatic neuroendocrine tumors (pNETs) represent a small part of pancreatic
neoplasms, and the knowledge about their indolent clinical course remains a subject of …

[HTML][HTML] Molecular biology of pancreatic neuroendocrine tumors: From mechanism to translation

X Shen, X Wang, X Lu, Y Zhao, W Guan - Frontiers in Oncology, 2022 - frontiersin.org
Pancreatic neuroendocrine tumors (pNETs) are a group of heterogeneous tumors originated
from progenitor cells. As these tumors are predominantly non-functional, most of them …

Molecular genetic studies of pancreatic neuroendocrine tumors: New therapeutic approaches

M Stevenson, KE Lines… - … and Metabolism Clinics, 2018 - endo.theclinics.com
Pancreatic neuroendocrine tumors (PNETs), which account for 1% to 2% of all pancreatic
neoplasms, are pathologically heterogeneous and consist of epithelial cells with phenotypic …

Genetics of pancreatic neuroendocrine tumors: implications for the clinic

A Pea, RH Hruban, LD Wood - Expert review of gastroenterology & …, 2015 - Taylor & Francis
Pancreatic neuroendocrine tumors (PanNETs) are a common and deadly neoplasm of the
pancreas. Although the importance of genetic alterations in PanNETs has been known for …

[HTML][HTML] DNA methylation patterns identify subgroups of pancreatic neuroendocrine tumors with clinical association

V Lakis, RT Lawlor, F Newell, AM Patch… - Communications …, 2021 - nature.com
Here we report the DNA methylation profile of 84 sporadic pancreatic neuroendocrine
tumors (PanNETs) with associated clinical and genomic information. We identified three …

Genetics and molecular pathology of neuroendocrine gastrointestinal and pancreatic tumors (gastroenteropancreatic neuroendocrine tumors)

K Öberg - Current Opinion in Endocrinology, Diabetes and …, 2009 - journals.lww.com
Molecular profiling of GEP-NETs demonstrates that pancreatic endocrine tumors and
gastrointestinal neuroendocrine tumors (carcinoids) display different genetic changes and …