Expiratory airway collapse is a characteristic feature in patients with chronic obstructive
pulmonary disease (COPD). We hypothesized that this collapse might mask the effects of …

It has been shown that patients with chronic obstructive pulmonary disease (COPD) develop
dynamic hyperinflation (DH), which contributes to dyspnoea and exercise intolerance …

Bronchodilator drugs produce variable improvements in forced expiratory volume in 1 s
(FEV1), but larger changes in end-expiratory lung volume (EELV) in chronic obstructive …

We tested the hypothesis that the decrease in dyspnea in patients with COPD with inhaled
albuterol is in part due to increased diaphragmatic contractility. Eleven patients with COPD …

Rationale: Exacerbation of chronic obstructive pulmonary disease commonly causes
hospitalization. The change in lung mechanics during exacerbation and its relationship to …

Expiratory flow limitation (EFL), which promotes dynamic hyperinflation and increased work
of breathing, often occurs in chronic obstructive pulmonary disease (COPD). The purpose of …

Study objectives Inspiratory capacity (IC) has been proposed as a simple method to assess
acute changes in functional residual capacity (FRC) with bronchodilation, assuming that …

Acute exacerbations of chronic obstructive disease (AECOPD) are characterised by
worsening dyspnoea that is variably prolonged. In this study, physiological changes during …

A significant proportion of patients with COPD show post-bronchodilator improvement in
lung volume even though this response is rarely considered when classifying subjects as …

Background We investigated whether a relationship between small airways dysfunction and
bronchodilator responsiveness exists in patients with chronic obstructive pulmonary disease …