The human innate regenerative ability is known to be limited by the intensity of the insult
together with the availability of progenitor cells, which may cause certain irreparable …

Tissue regeneration is rapidly evolving to treat anomalies in the entire human body. The
production of biodegradable, customizable scaffolds to achieve this clinical aim is …

Current treatments for diseases and trauma of dental, oral and craniofacial (DOC) structures
rely on durable materials such as amalgam and synthetic materials, or autologous tissue …

Facial deformities require precise reconstruction of the appearance and function of the
original tissue. The current standard of care—the use of bone harvested from another region …

Autogenous bone grafting remains a gold standard for the reconstruction critical-sized bone
defects in the craniomaxillofacial region. Nevertheless, this graft procedure has several …

Tissue-engineered oral mucosa, in the form of epithelial cell sheets or full-thickness oral
mucosa equivalents, is a potential solution for many patients with congenital defects or with …

Over the past two decades in situ tissue engineering has emerged as a new approach
where biomaterials are used to harness the body's own stem/progenitor cells to regenerate …

Combining stem cells with biomaterial scaffolds serves as a promising strategy for
engineering tissues for both in vitro and in vivo applications. This updated review details …

A majority of craniomaxillofacial reconstructive procedures are performed to replace or
construct missing or damaged skeletal structures. These operations require the harvesting of …

There is substantial need for the replacement of tissues in the craniofacial complex due to
congenital defects, disease, and injury. The field of tissue engineering, through the …