More than 85% of the global population requires repair or replacement of a craniofacial
structure. These defects range from simple tooth decay to radical oncologic craniofacial …

Tissue engineering (TE) is critical in oral and craniofacial reconstruction. One of the most
popular topics on the biomaterial-based tissue regeneration process may be the interaction …

Structured Abstract: Authors–Hollister SJ, Lin CY, Saito E, Lin CY, Schek RD, Taboas JM,
Williams JM, Partee B, Flanagan CL, Diggs A, Wilke EN, Van Lenthe GH, Müller R, Wirtz T …

Craniofacial injuries require a variety of different cell types to repopulate areas of bone,
cartilage, tendon, and fat. Mesenchymal stem cells (MSCs) provide a multipotent cell source …

The craniofacial region is anatomically complex and is of critical functional and cosmetic
importance, making reconstruction challenging. The limitations of current surgical options …

The treatment of oral and periodontal diseases and associated anomalies accounts for a
significant proportion of the healthcare burden, with the manifestations of these conditions …

Regeneration of normal shape, architecture, and function of craniofacial tissues following
congenital abnormality, trauma, or surgical treatment presents special problems to tissue …

Tissue-engineered approaches to regenerate bone in the craniomaxillofacial region utilize
biomaterial scaffolds to provide structural and biological cues to stem cells to stimulate …

Recent developments in craniofacial reconstruction have shown important advances in both
the materials and methods used. While autogenous tissue is still considered to be the gold …

Biomaterial design to repair craniomaxillofacial defects has largely focused on promoting
bone regeneration, while there are many additional factors that influence this process. The …