Facile synthesis and biological evaluation of chrysin derivatives

N Omonga, Z Zia, H Ghanbour… - Journal of Chemical …, 2021 - journals.sagepub.com
In this paper, novel synthetic methods, including microwave O-alkylation, were used to
produce several chrysin derivatives. These compounds were purified, characterised and …

[PDF][PDF] Synthesis of Some New Chrysin Derivatives and Their Biological Assessment as Antibacterial, Antibiofilm and Antifungal Agent.

S Bhowmik, T Das, S Ghosh, BK Sharma… - Asian Journal of …, 2018 - academia.edu
Some new derivatives of natural chrysin have been synthesized and evaluated for
antibacterial, antibiofilm and antifungal activities. Three compounds, namely 2a, 2e, 2i …

Synthesis and cytotoxicity of novel chrysin derivatives

K Hu, W Wang, H Cheng, SS Pan, J Ren - Medicinal Chemistry Research, 2011 - Springer
A series of chrysin derivatives 8a–8v were prepared and tested in vitro against HCT-116
(human colon cancer cell line), Hela (human cervical carcinoma cell line), DU-145 (human …

Synthesis and anticancer effect of chrysin derivatives

X Zheng, WD Meng, YY Xu, JG Cao, FL Qing - Bioorganic & Medicinal …, 2003 - Elsevier
A series of chrysin derivatives, prepared by alkylation, halogenation, nitration, methylation,
acetylation and trifluoromethylation, were tested in vitro against human gastric …

Synthesis and preliminary biological evaluation of chrysin derivatives as potential anticancer drugs.

X Zheng, FF Zhao, YM Liu, X Yao, ZT Zheng… - … (United Arab Emirates …, 2010 - europepmc.org
A series of chrysin derivatives were prepared from 2-hydroxyacetophenone, 2, 4-
dihydroxyacetophenone, 2, 4, 6-trihydroxy-acetophenone, using modified Baker …

Fluorine-containing chrysin derivatives: synthesis and biological activity

Y Zhu, X Yao, J Long, R Li, Y Liu… - Natural Product …, 2019 - journals.sagepub.com
Chrysin, a flavonoid, has played a great role in the fields of anticancer, antibacterial, and
antiviral drug discovery. A large number of chrysin derivatives have been synthesized …

[HTML][HTML] Synthesis and in vitro anticancer evaluation of novel chrysin and 7-aminochrysin derivatives

S Mayer, P Keglevich, P Ábrányi-Balogh, Á Szigetvári… - Molecules, 2020 - mdpi.com
Chrysin is a naturally occurring flavonoid with mild anticancer activity. In this paper we report
the synthesis of new chrysin derivatives alkylated with N-phenylchloroacetamides in position …

Synthesis and biological evaluation of novel C (7) modified chrysin analogues as antibacterial agents

KS Babu, TH Babu, PV Srinivas, KH Kishore… - Bioorganic & medicinal …, 2006 - Elsevier
The natural product, chrysin (5, 7-dihydroxy flavone), obtained from Oroxylum indicum,
exhibits numerous biological activities including anticancer, anti-inflammatory, and …

Synthesis and antitumor activity evaluation of chrysin derivatives

ZY Zhu, WX Wang, Z Wang, LJ Chen, JY Zhang… - European Journal of …, 2014 - Elsevier
Abstract A series of 5, 7-disubstituted chrysin, 7-monosubstituted chrysin, 5-monosubstituted
chrysin derivatives were synthesized by alkylation, acetylation, benzoylation …

Green Synthesis and Anticancer Evaluation of Novel Chrysin Hydrazone Derivatives

B Pouramiri, SR Seyedhosseini… - Polycyclic Aromatic …, 2023 - Taylor & Francis
Chrysin, a natural flavonoid, has been investigated for its anticancer biological properties.
Antifungal and anticancer properties of hydrazone derivatives have been proven. In this …