A tough polysaccharide-based cell-laden double-network hydrogel promotes articular cartilage tissue regeneration in rabbits

P Baei, H Daemi, F Mostafaei, FA Sayahpour… - Chemical Engineering …, 2021 - Elsevier
Hydrogels used for cartilage tissue engineering purposes must be designed to mimic the
biological and physical features of the native extracellular matrix (ECM). Here, we …

Self-crosslinking and injectable chondroitin sulfate/pullulan hydrogel for cartilage tissue engineering

T Li, X Song, C Weng, X Wang, L Sun, X Gong… - Applied Materials …, 2018 - Elsevier
Injectable hydrogels derived from natural polysaccharides have great application prospects
in cartilage tissue engineering (CTE). In this study, chondroitin sulfate was functionalized …

Double–network hydrogel based on exopolysaccharides as a biomimetic extracellular matrix to augment articular cartilage regeneration

Z Cai, Y Tang, Y Wei, P Wang, H Zhang - Acta Biomaterialia, 2022 - Elsevier
Cartilage regeneration remains a current challenge with no satisfactory strategy in surgery.
Hydrogels with structurally and biochemically biomimicking characteristics have been …

Injectable dual cross-linked adhesive hyaluronic acid multifunctional hydrogel scaffolds for potential applications in cartilage repair

C Yu, H Gao, Q Li, X Cao - Polymer Chemistry, 2020 - pubs.rsc.org
Injectable hydrogels have shown great potential for cartilage tissue engineering as three-
dimensional cell culture scaffolds, owing to their similarity to the extracellular matrix (ECM) …

Dynamic regulable sodium alginate/poly (γ-glutamic acid) hybrid hydrogels promoted chondrogenic differentiation of stem cells

P Wang, Y Pu, Y Ren, R Yang, W Zhang, X Tan… - Carbohydrate …, 2022 - Elsevier
Traditional hydrogels often fail to match the dynamic interactions between mechanical and
cellular behaviors exhibited by the natural cartilage extracellular matrix. In this research, we …

Biomimetic bacterial cellulose-enhanced double-network hydrogel with excellent mechanical properties applied for the osteochondral defect repair

X Zhu, T Chen, B Feng, J Weng, K Duan… - ACS Biomaterials …, 2018 - ACS Publications
Although hydrogels based on biopolymers show many advantages, their low mechanical
properties limit their applications in osteochondral tissue engineering. In this study, one part …

Self-crosslinking and injectable hyaluronic acid/RGD-functionalized pectin hydrogel for cartilage tissue engineering

F Chen, Y Ni, B Liu, T Zhou, C Yu, Y Su, X Zhu… - Carbohydrate …, 2017 - Elsevier
In the present study, we developed a biomimetic injectable hydrogel system based on
hyaluronic acid-adipic dihydrazide and the oligopeptide G 4 RGDS-grafted oxidized pectin …

A tough double network hydrogel for cartilage tissue engineering

C Fan, L Liao, C Zhang, L Liu - Journal of Materials Chemistry B, 2013 - pubs.rsc.org
To develop hydrogels with high mechanical strength for cell encapsulation and three-
dimensional culture is a critical challenge for cartilage tissue engineering. In this study …

Nano-hydroxyapatite enhanced double network hydrogels with excellent mechanical properties for potential application in cartilage repair

S Gan, W Lin, Y Zou, B Xu, X Zhang, J Zhao… - Carbohydrate …, 2020 - Elsevier
Hydrogels with desirable characteristics have been supposed to be potential materials for
cartilage repair. However, the biomechanical, biotribological and biocompatible properties …

[HTML][HTML] Synergistic chondrogenesis promotion and arthroscopic articular cartilage restoration via injectable dual-drug-loaded sulfated hyaluronic acid hydrogel for …

W Gao, K Chen, W He, S Zhao, D Cui, C Tao… - Composites Part B …, 2023 - Elsevier
Bone marrow stem cells (BMSCs)-loaded injectable hydrogels are promising vehicles for the
restoration of articular cartilage defect (ACD), while was limited with insufficient …