Gene therapy has been experiencing a breakthrough in recent years, targeting various
specific cell groups in numerous therapeutic areas. However, most recent clinical studies …

Non-viral vectors are simple in theory but complex in practice. Apart from intra cellular and
extracellular barriers, number of other challenges also needs to be overcome in order to …

Efficient delivery of genetic material into cells is a critical process to translate gene therapy
into clinical practice. In this sense, the increased knowledge acquired during past years in …

Gene therapy encompasses the transfer of exogenous genetic materials into the patient's
target cells to treat or prevent diseases. Nevertheless, the transfer of genetic material into …

Gene therapy is manipulation in/of gene expression in specific cells/tissue to treat diseases.
This manipulation is carried out by introducing exogenous nucleic acids, such as DNA or …

Over the past few decades, gene therapy has gained immense importance in medical
research as a promising treatment strategy for diseases such as cancer, AIDS, Alzheimer's …

Gene delivery has attracted increasing interest as a highly promising therapeutic method to
treat various diseases, including both genetic and acquired disorders. Viral-vectors based …

The promise of cancer gene therapeutics is hampered by difficulties in the in vivo delivery to
the targeted tumor cells, and systemic delivery remains to be the biggest challenge to be …

Gene therapy has been deemed the medicine of the future due to its potential to treat many
types of diseases. However, many obstacles remain before gene delivery is optimized to …

Gene therapy is becoming a promising therapeutic modality for the treatment of genetic and
acquired disorders. Nonviral approaches as alternative gene transfer vehicles to the popular …