Allostatic load has been proposed as a cumulative measure of dysregulation across multiple
physiological systems, and has been postulated to impact health risks. In the allostatic load …

Allostatic load (AL) has been proposed as a new conceptualization of cumulative biological
burden exacted on the body through attempts to adapt to life's demands. Using a …

Objectives: To study the association between change in allostatic load (a risk score
constructed from multiple biological markers) over a 2.5-year period and mortality in the …

The theory of allostatic load [McEwen, BS, Stellar, E., 1993. Stress and the individual:
mechanisms leading to disease. Arch. Intern. Med. 153, 2093–2101] describes how the …

Background: Exponential growth in the population of older adults presents clinicians with
special concerns about factors affecting risks for declines in cognitive and physical …

OBJECTIVES: To examine the association between allostatic load (AL), an index of
multisystem physiological dysregulation, and frailty development over a 3‐year follow‐up in …

Since its inception in the 1980s, through further developments during the 1990s, and
continuing today, the paradigm of allostatic load (AL) has becomed an important paradigm …

The allostatic load framework postulates that an important pathway connecting the social
environment with health involves biological responses to stressful stimuli and the …

Allostatic load is a multiple biomarker measure of physiological 'wear and tear'that has
shown some promise as marker of overall physiological health, but its power as a risk …

Allostatic load represents the strain that chronic stress exerts on interconnected biological
systems. Associated algorithms are related to numerous deleterious physical outcomes in …