Aggressive pharmacologic donor management results in more transplanted organs1
JD Rosendale, HM Kauffman, MA McBride… - …, 2003 - journals.lww.com
Background. Brain death results in adverse pathophysiologic effects in many cadaveric
donors, resulting in cardiovascular instability and poor organ perfusion. Hormonal …
donors, resulting in cardiovascular instability and poor organ perfusion. Hormonal …
Hormonal resuscitation yields more transplanted hearts, with improved early function1
JD Rosendale, HM Kauffman, MA McBride… - …, 2003 - journals.lww.com
Background. Brain death results in cardiovascular instability and poor organ perfusion in
many brain-dead donors. Hormonal resuscitation stabilizes certain brain-dead donors and is …
many brain-dead donors. Hormonal resuscitation stabilizes certain brain-dead donors and is …
Using thyroid hormone in brain‐dead donors to maximize the number of organs available for transplantation
The aggressive management of brain‐dead (cadaveric) organ donors has been shown to
increase organs available for transplantation. Some centers use hormone therapy with …
increase organs available for transplantation. Some centers use hormone therapy with …
[HTML][HTML] Intravenous levothyroxine for unstable brain-dead heart donors
R Dhar, GF Marklin, WD Klinkenberg… - … England Journal of …, 2023 - Mass Medical Soc
Background Hemodynamic instability and myocardial dysfunction are major factors
preventing the transplantation of hearts from organ donors after brain death. Intravenous …
preventing the transplantation of hearts from organ donors after brain death. Intravenous …
Intensivist‐led management of brain‐dead donors is associated with an increase in organ recovery for transplantation
The disparity between the number of patients in need of organ transplantation and the
number of available organs is steadily rising. We hypothesized that intensivist‐led …
number of available organs is steadily rising. We hypothesized that intensivist‐led …
Hormonal therapy of the brain-dead organ donor: experimental and clinical studies
D Novitzky, DKC Cooper, JD Rosendale… - …, 2006 - journals.lww.com
Abstract Experiments in Cape Town in the 1980s demonstrated that acute brain death is
followed by massive catecholamine release resulting in systemic hypertension, acute left …
followed by massive catecholamine release resulting in systemic hypertension, acute left …
Care of the potential organ donor
KE Wood, BN Becker, JG McCartney… - … England Journal of …, 2004 - Mass Medical Soc
Organ transplantation often depends on obtaining functioning organs from a donor who has
recently died. This review presents a structured approach to management of the care of the …
recently died. This review presents a structured approach to management of the care of the …
Complications of brain death: frequency and impact on organ retrieval
A Salim, M Martin, C Brown, H Belzberg… - The American …, 2006 - journals.sagepub.com
Brain death is associated with complex hemodynamic, endocrine, and metabolic dysfunction
that can lead to major complications with the potential donor. Untreated, this can progress to …
that can lead to major complications with the potential donor. Untreated, this can progress to …
Thyroid hormone therapy in the management of 63,593 brain-dead organ donors: a retrospective analysis
D Novitzky, Z Mi, Q Sun, JF Collins… - Transplantation, 2014 - journals.lww.com
Background Hormonal therapy to the brain-dead potential organ donor can include thyroid
hormone (triiodothyronine [T 3] or levothyroxine [T 4]), corticosteroids, antidiuretic hormone …
hormone (triiodothyronine [T 3] or levothyroxine [T 4]), corticosteroids, antidiuretic hormone …
The role of thyroid hormone administration in potential organ donors
A Salim, P Vassiliu, GC Velmahos, J Sava… - Archives of …, 2001 - jamanetwork.com
Hypothesis Levothyroxine sodium therapy should be used in brain-dead potential organ
donors to reverse hemodynamic instability and to prevent cardiovascular collapse, leading …
donors to reverse hemodynamic instability and to prevent cardiovascular collapse, leading …