Background. Brain death results in adverse pathophysiologic effects in many cadaveric
donors, resulting in cardiovascular instability and poor organ perfusion. Hormonal …

Background. Brain death results in cardiovascular instability and poor organ perfusion in
many brain-dead donors. Hormonal resuscitation stabilizes certain brain-dead donors and is …

The aggressive management of brain‐dead (cadaveric) organ donors has been shown to
increase organs available for transplantation. Some centers use hormone therapy with …

Background Hemodynamic instability and myocardial dysfunction are major factors
preventing the transplantation of hearts from organ donors after brain death. Intravenous …

The disparity between the number of patients in need of organ transplantation and the
number of available organs is steadily rising. We hypothesized that intensivist‐led …

Abstract Experiments in Cape Town in the 1980s demonstrated that acute brain death is
followed by massive catecholamine release resulting in systemic hypertension, acute left …

Organ transplantation often depends on obtaining functioning organs from a donor who has
recently died. This review presents a structured approach to management of the care of the …

Brain death is associated with complex hemodynamic, endocrine, and metabolic dysfunction
that can lead to major complications with the potential donor. Untreated, this can progress to …

Background Hormonal therapy to the brain-dead potential organ donor can include thyroid
hormone (triiodothyronine [T 3] or levothyroxine [T 4]), corticosteroids, antidiuretic hormone …

Hypothesis Levothyroxine sodium therapy should be used in brain-dead potential organ
donors to reverse hemodynamic instability and to prevent cardiovascular collapse, leading …