Susceptibility of cytotoxic T lymphocyte (CTL) clones to inhibition by anti-T3 and anti-T4 (but not anti-LFA-1) monoclonal antibodies varies with the" avidity" of CTL …

S Shaw, G Goldstein, TA Springer… - Journal of immunology …, 1985 - journals.aai.org
To explore the role of the T3, T4, and LFA-1 molecules in high and low" avidity" interactions
between SB2-specific cytotoxic T lymphocyte (CTL) clones and their targets, monoclonal …

Characterization of anti-CD8-resistant cytolytic T lymphocytes induced by multivalent cross-linking of CD8 on precursor cells.

SA McCarthy, E Kaldjian, A Singer - Journal of immunology …, 1989 - journals.aai.org
The lytic activity of most CD8+ MHC class I allospecific CTL generated in vitro can be
inhibited by anti-CD8 antibodies. Such inhibition has led to hypotheses that CD8/class I …

Modulation of lymphokine release and cytolytic activities by activating peripheral blood lymphocytes via CD2.

H Valentin, H Groux, C Gelin, I Chretien… - Journal of immunology …, 1990 - journals.aai.org
We had previously shown that the signal of activation delivered via CD2 varies according to
the mitogenic pair of CD2 mAb used. We had selected two typical mAb pairs, D66+ T11 (1) …

GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO: II. EFFECT OF REPEATED EXPOSURE TO ALLOANTIGENS ON THE CYTOTOXIC ACTIVITY OF LONG-TERM MIXED L …

HR MacDonald, HD Engers, JC Cerottini… - The Journal of …, 1974 - rupress.org
Mouse cytotoxic T lymphocytes (CTL) were generated in unidirectional mixed leukocyte
cultures (MLC) using normal C57BL/6 spleen cells as responding cells and irradiated DBA/2 …

Inhibition of human killer cells by autologous lymphocytes

SB Pollack, SL Emmons - The Journal of Immunology, 1979 - journals.aai.org
Human antibody-dependent cellular cytotoxicity (ADCC) mediated by K cells is shown in this
study to be inhibited by autologous lymphocytes. Inhibitor activity resides in a population of …

Cytotoxic lymphocytes induced by soluble factors derived from the medium of leukocyte cultures

S Kasakura - The Journal of Immunology, 1977 - journals.aai.org
Studies were undertaken to evaluate the cytotoxic capacity of human peripheral blood
lymphocytes activated by either supernatants (CFM) derived from lymphocyte cultures or …

Human cytotoxic T cell structures associated with expression of cytolysis. I. Analysis at the clonal cell level of the cytolysis‐inhibiting effect of 7 monoclonal antibodies

B Malissen, N Rebai, A Liabeuf… - European Journal of …, 1982 - Wiley Online Library
Monoclonal antibodies (mAb) derived from BALB/c mice immunized with human anti‐HLA‐
A2 cloned cytotoxic T lymphocytes (CTL) were screened for their ability to block, in the …

Studies on the mechanism of suppression of primary cytotoxic responses by cloned cytotoxic T lymphocytes.

PJ Fink, HG Rammensee, JD Benedetto… - … (Baltimore, Md.: 1950 …, 1984 - journals.aai.org
We have shown in the accompanying companion paper that cloned cytotoxic T lymphocytes
(CTL) can serve as veto cells in vitro, suppressing primary cytotoxic activity directed against …

Human monocyte-mediated cytotoxicity: the use of Ig-bearing hybridomas as target cells to detect trigger molecules on the monocyte cell surface.

RF Graziano, MW Fanger - Journal of immunology (Baltimore, Md …, 1987 - journals.aai.org
We recently reported the preparation and characterization of a monoclonal antibody, 32.2,
specific for the high-affinity Fc receptor (FcR) for IgG on human monocytes. We have utilized …

Rapidly expanded activated human killer cell clones have strong antitumor cell activity and have the surface phenotype of either T gamma, T-non-gamma, or null cells.

RJ Van de Griend, BA Van Krimpen… - … (Baltimore, Md.: 1950 …, 1984 - journals.aai.org
Cloned lymphoid cell lines showing cytolytic activity were derived from natural killer (NK) cell-
enriched cell fractions obtained by fluorescence-activated cell sorting of cells that reacted …