Nucleic Acid Testing for Human Disease describes various techniques including target and
signal amplification-based NAT procedures, microarrays, bead-based multiplex assays, in …

Timely and accurate detection of the causal agent of a disease is crucial to restrict suffering
and save lives. Mere symptoms are often not enough to detect the root cause of the disease …

Molecular Diagnosis Page 1 Page 2 Molecular Diagnosis Page 3 THE MEDICAL PERSPECTIVES
SERIES Advisors: B. David Hames Schaa/ af Biachemistry and Ma/ecu/ar Bia/agy, University af …

Molecular biology has revolutionized the understanding of many aspects of human disease.
Ongoing developments in DNA diagnostics—the analysis of disease at the nucleic acid level …

BioTechniques 32: S4-S13 (June 2002) la Vega et al., this Supplement), molecular beacons
(54) nuclease-(16) and structure-specific nuclease invader technology (13, 40; M. de Arruda …

Publisher Summary This chapter discusses the evolution of molecular or nucleic acid-based
diagnosis of human disorders. Molecular diagnostics is the detection of various pathogenic …

BACKGROUND Effective upstream preparation of nucleic acid (NA) is important for
molecular techniques that detect unique DNA or RNA sequences. The isolated NA should …

This chapter focuses on signal amplification technologies. It reviews the molecular bases
and inherent properties of the signal amplification technologies that support the many …

Meet the challenges of this rapidly expanding field with a solid understanding of the
fundamentals of nucleic acid biochemistry as well as the advanced concepts integral to …

The complexity of Nucleic acid Amplification Technology (NAT1), comprising sample
preparation, amplification and detection methods, requires specific design considerations for …