Staphylococcus aureus biofilm: a complex developmental organism

DE Moormeier, KW Bayles - Molecular microbiology, 2017 - Wiley Online Library
Chronic biofilm‐associated infections caused by Staphylococcus aureus often lead to
significant increases in morbidity and mortality, particularly when associated with indwelling …

Staphylococcal biofilm development: structure, regulation, and treatment strategies

K Schilcher, AR Horswill - Microbiology and Molecular Biology …, 2020 - Am Soc Microbiol
In many natural and clinical settings, bacteria are associated with some type of biotic or
abiotic surface that enables them to form biofilms, a multicellular lifestyle with bacteria …

Biofilm Formation by Pathogenic Bacteria: Applying a Staphylococcus aureus Model to Appraise Potential Targets for Therapeutic Intervention

Z Sedarat, AW Taylor-Robinson - Pathogens, 2022 - mdpi.com
Carried in the nasal passages by up to 30% of humans, Staphylococcus aureus is
recognized to be a successful opportunistic pathogen. It is a frequent cause of infections of …

Staphylococcus aureus biofilms: Properties, regulation, and roles in human disease

NK Archer, MJ Mazaitis, JW Costerton, JG Leid… - Virulence, 2011 - Taylor & Francis
Increasing attention has been focused on understanding bacterial biofilms and this growth
modality's relation to human disease. In this review we explore the genetic regulation and …

The extracellular matrix of Staphylococcus aureus biofilms comprises cytoplasmic proteins that associate with the cell surface in response to decreasing pH

L Foulston, AKW Elsholz, AS DeFrancesco, R Losick - MBio, 2014 - Am Soc Microbiol
Biofilm formation by Staphylococcus aureus involves the formation of an extracellular matrix,
but the composition of this matrix has been uncertain. Here we report that the matrix is …

The role of biofilms in persistent infections and factors involved in ica-independent biofilm development and gene regulation in Staphylococcus aureus

AMS Figueiredo, FA Ferreira, CO Beltrame… - Critical Reviews in …, 2017 - Taylor & Francis
Staphylococcus aureus biofilms represent a unique micro-environment that directly
contribute to the bacterial fitness within hospital settings. The accumulation of this structure …

Environmental factors modulate biofilm formation by Staphylococcus aureus

Y Liu, J Zhang, Y Ji - Science Progress, 2020 - journals.sagepub.com
Biofilm formation on indwelling medical devices represents an exclusive evasion
mechanism for many pathogenic bacteria to establish chronic infections. Staphylococcus …

Biology and regulation of staphylococcal biofilm

P François, J Schrenzel, F Götz - International journal of molecular …, 2023 - mdpi.com
Despite continuing progress in medical and surgical procedures, staphylococci remain the
major Gram-positive bacterial pathogens that cause a wide spectrum of diseases, especially …

Staphylococcal infections: mechanisms of biofilm maturation and detachment as critical determinants of pathogenicity

M Otto - Annual review of medicine, 2013 - annualreviews.org
Biofilm-associated infections are a significant cause of morbidity and death. Staphylococci,
above all Staphylococcus aureus and S. epidermidis, are the most frequent causes of biofilm …

Staphylococcal biofilms

M Otto - Microbiology spectrum, 2018 - Am Soc Microbiol
Staphylococci, with the leading species Staphylococcus aureus and Staphylococcus
epidermidis, are the most frequent causes of infections on indwelling medical devices. The …