Plant-based drugs have been used for centuries for treating different ailments. Malaria, one
of the prevalent threats in many parts of the world, is treated mainly by artemisinin-based …

To study the pharmacokinetic profile of artemether in children and in the context of antiviral
drugs for HIV infected patients co-infected with malaria, an LC-MS/MS method was …

Dihydroartemisinin (DHA) and its' derivatives have been employed as the most powerful first-
line drugs for malarial treatment for several decades. The metabolism of DHA has not been …

A sensitive and selective method is described for the determination of artemether and its
active dihydroartemisinin metabolite in human plasma using artemisinin as internal …

Concurrent administration of aqueous extract of C. sanguinolenta was earlier reported to
alter the pharmacokinetics of artesunate consequently resulting in an increase in the …

Malaria is a global health problem leading to the death of 435,000 cases in tropical and sub-
tropical zones. Spread and emergence of increasing resistance to the antimalarial drugs are …

Background Artemisinin derivatives are used in antimalarial drug combination therapy.
Artemisinin and piperaquine have recently been proven to be prospective candidates for …

Artemisinin has been proven to be an effective antimalarial compound, especially for
chloroquine-resistant and cerebral malaria. However, its biosynthesis pathway is still not …

Background: Artemether–lumefantrine is the most widely recommended artemisinin-based
combination treatment for falciparum malaria. Quantification of artemether and its metabolite …

Artemisinin a natural sesquiterpenoid isolated from Artemisia annua, is of great interest in
the treatment of malaria. In this study important artemisinin and related metabolites were …