[HTML][HTML] Eupalinolide O, a novel sesquiterpene lactone from Eupatorium lindleyanum DC., induces cell cycle arrest and apoptosis in human MDA-MB-468 breast …

B Yang, Y Zhao, C Lou, H Zhao - Oncology Reports, 2016 - spandidos-publications.com
Sesquiterpene lactones have been confirmed to have potential antitumor activity. Here, we
demonstrated that Eupalinolide O (EO), a novel sesquiterpene lactone isolated from …

Eupalinolide J induces apoptosis, cell cycle arrest, mitochondrial membrane potential disruption and DNA damage in human prostate cancer cells

Z Wu, X Xu, L Dai, Y Wang, B Yang… - The Journal of …, 2020 - jstage.jst.go.jp
Eupalinolide J (EJ) is a new sesquiterpene lactone isolated from Eupatorium lindleyanum
DC. In the present study, we investigated the anti-cancer activity of EJ on cell proliferation in …

New 6(17)-epoxylathyrane diterpene: aellinane from Euphorbia aellenii induces apoptosis via mitochondrial pathway in ovarian cancer cell line

F Nabatchian, A Moradi, M Aghaei… - Toxicology …, 2017 - Taylor & Francis
Euphorbia species have been used in traditional medicine in many countries for the
treatment of cancer. This article aims to evaluate the capability of a new lathyrane diterpene …

Isocostunolide, a sesquiterpene lactone, induces mitochondrial membrane depolarization and caspase-dependent apoptosis in human melanoma cells

CN Chen, HH Huang, CL Wu, CPC Lin, JTA Hsu… - Cancer letters, 2007 - Elsevier
Isocostunolide is a sesquiterpene lactone isolated from the roots of Inula helenium. Its
chemical structure was determined by NMR and FAB-MS spectra. No biological activities of …

1-oxoeudesm-11 (13)-ene-12, 8α-lactone-induced apoptosis via ROS generation and mitochondria activation in MCF-7 cells

M Cui, Y Zhang, S Liu, W Xie, M Ji, H Lou… - Archives of pharmacal …, 2011 - Springer
A novel eudesmane-type sesquiterpene compound, 1-oxoeudesm-11 (13)-eno-12, 8a-
lactone (OEL), was isolated from Aster himalaicus. Its effect on apoptosis in human breast …

[PDF][PDF] Eupatilin: A flavonoid compound isolated from the artemisia plant, induces apoptosis and G2/M phase cell cycle arrest in human melanoma A375 cells

AA Shawi, A Rasul, M Khan, F Iqbal… - Afr. J. Pharm …, 2011 - academicjournals.org
Eupatilin is a flavonoid compound isolated from the Artemisia plant. Eupitillin possesses
antioxidant as well as potent anticancer properties. In this study, for the first time, we …

Eupalinolide O Induces Apoptosis in Human Triple‐Negative Breast Cancer Cells via Modulating ROS Generation and Akt/p38 MAPK Signaling Pathway

Y Zhao, L Fu, J Chen, J Zhou, C Tian… - Journal of …, 2022 - Wiley Online Library
Background. Triple‐negative breast cancer (TNBC) is a subtype of breast cancer with limited
therapeutic options. Eupalinolide O (EO) was reported to inhibit tumor growth. This study is …

β‐Eudesmol induces JNK‐dependent apoptosis through the mitochondrial pathway in HL60 cells

Y Li, T Li, C Miao, J Li, W Xiao, E Ma - Phytotherapy Research, 2013 - Wiley Online Library
β‐eudesmol, a natural sesquiterpenol present in a variety of Chinese herbs, is known to
inhibit the proliferation of human tumor cells. However, the molecular mechanisms of the …

Ebracteolatain A exerts anti-proliferation of breast cancer by inhibiting Protein kinase D 1 in MEK/ERK and PI3K/AKT signaling pathways

C Li, Y Wang, C Wu, J Zhou, Y Zhou, Y Jiao, Y Li… - Phytomedicine, 2023 - Elsevier
Abstract Background Ebracteolatain A (EA) is an acetyl-phloroglucinol compound extracted
from Euphorbiae Ebracteolatae Radix, which has been shown to have antitumor activity …

Anticancer activity of oleiferoside B involving autophagy and apoptosis through increasing ROS release in MCF-7 cells and SMMC-7721 cells

S Feng, Z Zha, Z Wang, P Yang, J Wu, X Li… - Natural Product …, 2021 - Taylor & Francis
Oleiferoside B is a triterpenoid monomer compound, mainly isolated from roots of Camellia
oleifera Abel, the underlying mechanism of its antitumour is not clear. In the present study …