[HTML][HTML] Mutations of the TERT promoter are associated with aggressiveness and recurrence/distant metastasis of papillary thyroid carcinoma

R Liu, Y Li, W Chen, J Cong, Z Zhang… - Oncology …, 2020 - spandidos-publications.com
Several previous studies have shown that mutations in B‑Raf proto‑oncogene (BRAF) and
telomerase reverse transcriptase (TERT) can be used for the diagnosis and prognosis of …

[HTML][HTML] BRAF and TERT promoter mutations in the aggressiveness of papillary thyroid carcinoma: a study of 653 patients

L Jin, E Chen, S Dong, Y Cai, X Zhang, Y Zhou… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The role of telomerase reverse transcriptase (TERT) gene promoter mutations in the
aggressiveness of papillary thyroid cancer (PTC) remains to be further investigated. Here we …

TERT promoter mutations are associated with distant metastases in papillary thyroid carcinoma

G Gandolfi, M Ragazzi, A Frasoldati… - European Journal of …, 2015 - academic.oup.com
Objective Transcriptional activating mutations in the promoter of the telomerase reverse
transcriptase (TERT) gene were reported at high frequency in aggressive poorly …

Co-existence of BRAFV600E and TERT promoter mutations in papillary thyroid carcinoma is associated with tumor aggressiveness, but not with lymph node …

H Ren, Y Shen, D Hu, W He, J Zhou, Y Cao… - Cancer management …, 2018 - Taylor & Francis
Background Mutations of BRAF V600E and TERT promoters are associated with thyroid
cancer development. This study further investigated association of these mutations with …

Role of molecular markers to predict distant metastasis in papillary thyroid carcinoma: Promising value of TERT promoter mutations and insignificant role of BRAF …

HG Vuong, AMA Altibi, UNP Duong, HTT Ngo… - Tumor …, 2017 - journals.sagepub.com
The presence of distant metastasis is associated with an adverse outcome in papillary
thyroid cancer. We performed a meta-analysis to investigate the role of molecular markers …

TERT mRNA Expression as a Novel Prognostic Marker in Papillary Thyroid Carcinomas

A Tanaka, M Matsuse, V Saenko, T Nakao… - Thyroid, 2019 - liebertpub.com
Background: Telomerase reverse transcriptase (TERT) promoter mutations have been found
in a subset of papillary thyroid carcinomas (PTCs) and are associated with tumor …

[HTML][HTML] TERT promoter and BRAF V600E mutations in papillary thyroid cancer: a single-institution experience in Korea

MJ Kim, JK Kim, GJ Kim, SW Kang, J Lee, JJ Jeong… - Cancers, 2022 - mdpi.com
Simple Summary TERT promoter mutation has recently emerged as a promising prognostic
biomarker for aggressive papillary thyroid cancer (PTC), along with BRAF B600E mutation …

[HTML][HTML] TERT promoter Mutation and Its Association with Clinicopathological Features and Prognosis of Papillary Thyroid Cancer: A Meta-analysis

C Liu, Z Liu, T Chen, W Zeng, Y Guo, T Huang - Scientific reports, 2016 - nature.com
We performed a meta-analysis to elucidate the associations of the clinicopathological
characteristics and prognostic factors of papillary thyroid cancer (PTC) with TERT promoter …

BRAF V600E and TERT Promoter Mutations Cooperatively Identify the Most Aggressive Papillary Thyroid Cancer With Highest Recurrence

M Xing, R Liu, X Liu, AK Murugan, G Zhu… - Journal of clinical …, 2014 - ascopubs.org
Purpose To investigate the prognostic value of the BRAF V600E mutation and the recently
identified TERT promoter mutation chr5: 1,295,228 C> T (C228T), individually and in their …

Prognostic implication of BRAF and TERT promoter mutation combination in papillary thyroid carcinoma—a meta‐analysis

HG Vuong, AMA Altibi, UNP Duong… - Clinical …, 2017 - Wiley Online Library
Introduction The use of molecular markers, especially BRAF and TERT promoter mutations,
for risk stratification in papillary thyroid carcinoma (PTC) is subject to continuing debate. In …