Clinical evaluation of laboratory methods to monitor exposure of rivaroxaban at trough and peak in patients with atrial fibrillation

F Al-Aieshy, RE Malmström, J Antovic… - European journal of …, 2016 - Springer
Purpose The one-dose daily regime of rivaroxaban could cause a pronounced variability in
concentration and effect of which a deeper knowledge is warranted. This study aimed to …

[HTML][HTML] Reduced-Dose Rivaroxaban Is Associated with Lower All-Cause Mortality in Older Patients with Nonvalvular Atrial Fibrillation

WR Chiou, MI Su, YH Lee, PL Lin, CW Liu - Journal of Clinical Medicine, 2023 - mdpi.com
Background: Reduced-dose rivaroxaban (10 mg) was used in the J-ROCKET AF trial,
demonstrating safety in the Asian population. It remains unclear whether treatment with …

Intra-and inter-individual rivaroxaban concentrations and potential bleeding risk in patients with atrial fibrillation

M Miklič, A Mavri, N Vene, L Söderblom… - European Journal of …, 2019 - Springer
Background Routine laboratory monitoring of rivaroxaban and dose adjustment relating to
exposure is currently not recommended. However, in certain clinical situations, assessment …

[HTML][HTML] Impact of rivaroxaban compared with warfarin on the coagulation status in Japanese patients with non-valvular atrial fibrillation: a preliminary analysis of the …

K Tajiri, A Sato, T Harunari, N Shimojo, I Yamaguchi… - Journal of …, 2015 - Elsevier
Background Rivaroxaban is an oral anticoagulant that effectively prevents thromboembolic
complications using fixed doses without requiring laboratory monitoring. In this study, we …

Clinical safety outcomes in patients with nonvalvular atrial fibrillation on rivaroxaban and diltiazem

JW Bartlett, E Renner, E Mouland… - Annals of …, 2019 - journals.sagepub.com
Background: It is unknown whether diltiazem, a moderate cytochrome P450 enzyme
(CYP3A4) and P-glycoprotein (P-gp) inhibitor, increases the incidence of bleeding events in …

Rivaroxaban versus warfarin in Chinese elder diabetic patients with non-valvular atrial fibrillation: a retrospective study on the effectiveness and associated risks (EAR …

S Wang, R Qiang, H Zhang - Tropical Journal of Pharmaceutical Research, 2020 - ajol.info
Purpose: To evaluate the effectiveness and associated risks of rivaroxaban against warfarin
in Chinese elderly diabetic patients with non-valvular atrial fibrillation. Methods: Data …

Population pharmacokinetic and pharmacodynamic analysis of rivaroxaban in Chinese patients with non-valvular atrial fibrillation

X Liu, Y Zhang, H Ding, M Yan, Z Jiao… - Acta Pharmacologica …, 2022 - nature.com
Rivaroxaban, a direct factor Xa inhibitor, is widely used for stroke prevention in patients with
non-valvular atrial fibrillation (NVAF). The aim of this study was to conduct a population …

An analysis on distribution and inter-relationships of biomarkers under rivaroxaban in Japanese patients with non-valvular atrial fibrillation (CVI ARO 1)

S Suzuki, T Yamashita, H Kasai, T Otsuka… - Drug Metabolism and …, 2018 - Elsevier
Prothrombin time (PT) has been widely used for measuring anticoagulation intensity under
rivaroxaban therapy, but precise information has not been well established yet. Consecutive …

Initial rivaroxaban dosing in patients with atrial fibrillation

K Ablefoni, A Buchholz, L Ueberham… - Clinical …, 2019 - Wiley Online Library
Background Rivaroxaban is a non‐vitamin K oral anticoagulant and has been approved for
prevention of stroke and systemic embolism in patients with non‐valvular atrial fibrillation …

Clinical profile, management and outcomes in a cohort of elderly and highly comorbid patients with nonvalvular atrial fibrillation treated with rivaroxaban in routine …

DB Guinda, ÓC García, JO Pérez, MG Aznarez… - Future …, 2018 - Taylor & Francis
Aim: To analyze clinical profile and management of patients with nonvalvular atrial
fibrillation treated with rivaroxaban in clinical practice according to age and to ascertain …