Introduction Chronic exposure to stress has been shown to impact a wide range of health-
related outcomes in older adults. Despite extensive animal literature revealing deleterious …

Hippocampal volume has been found to be smaller in individuals with stress-related
disorders, but it remains unclear whether smaller volume is a consequence of stress or …

Aim Major depression is associated with hippocampal volume changes, especially in late‐
life depression. These changes usually consist of volume reductions, but depression‐related …

Introduction: Several of the brain regions vulnerable to increased levels of stress (ie,
hippocampus and prefrontal cortex) are also known to undergo disproportionate decline …

Major depressive disorder is associated with smaller hippocampal volumes but the
mechanisms underlying this relationship are unclear. To examine the effect of environmental …

Mixed findings have been reported on the relationship between hippocampal integrity and
major depression in clinical populations. Few neuroimaging studies have investigated …

The hypothalamic pituitary adrenal axis production of the stress hormone cortisol interacts
with the hippocampal formation and impacts memory function. A growing interest is to …

In aged and pathological populations, reduced hippocampal volume is frequently described
in association with impairment of hippocampus-dependent cognitive processes and …

Specific subfields within the hippocampus have shown vulnerability to chronic stress,
highlighting the importance of looking regionally within the hippocampus to understand the …

Objective: Research has shown that depression is a risk factor for Alzheimer's disease (AD)
and subsequent cognitive decline. This is compounded by evidence showing an association …