Selectin binding is essential for peritoneal carcinomatosis in a xenograft model of human pancreatic adenocarcinoma in pfp−−/rag2−− mice

F Gebauer, D Wicklein, K Stübke, N Nehmann… - Gut, 2013 - gut.bmj.com
Background and objective E-and P-selectins expressed on the luminal surface of
mesodermally derived endothelial cells play a crucial role in the formation of …

The role of immunoglobulin superfamily cell adhesion molecules in cancer metastasis

C Wai Wong, DE Dye… - International journal of cell …, 2012 - Wiley Online Library
Metastasis is a major clinical problem and results in a poor prognosis for most cancers. The
metastatic pathway describes the process by which cancer cells give rise to a metastatic …

Cell–cell and cell–matrix dynamics in intraperitoneal cancer metastasis

KL Sodek, KJ Murphy, TJ Brown… - Cancer and Metastasis …, 2012 - Springer
The peritoneal metastatic route of cancer dissemination is shared by cancers of the ovary
and gastrointestinal tract. Once initiated, peritoneal metastasis typically proceeds rapidly in a …

Mechanisms of metastasis in colorectal cancer and metastatic organotropism: hematogenous versus peritoneal spread

E Pretzsch, F Bösch, J Neumann… - Journal of …, 2019 - Wiley Online Library
Metastasis is the major cause of death in patients with colorectal carcinoma (CRC). The
most common sites of metastasis are the liver and the peritoneum. Peritoneal …

Oxidative stress‐dependent increase in ICAM‐1 expression promotes adhesion of colorectal and pancreatic cancers to the senescent peritoneal mesothelium

K Ksia̧żek, J Mikuła‐Pietrasik, R Catar… - … journal of cancer, 2010 - Wiley Online Library
Abstract Intercellular adhesion molecule‐1 (ICAM‐1) has been implicated in adhesion of
colorectal and pancreatic cancer cells (of the SW480 and PSN‐1 line, respectively) to the …

In search for optimal targets for intraoperative fluorescence imaging of peritoneal metastasis from colorectal cancer

CES Hoogstins, B Weixler, LSF Boogerd… - Biomarkers in …, 2017 - journals.sagepub.com
Peritoneal metastasis (PM) occurs in about 10% of patients with colorectal cancer (CRC).
Fluorescence imaging can enhance contrast between cancerous and benign tissue …

Cadherin composition and multicellular aggregate invasion in organotypic models of epithelial ovarian cancer intraperitoneal metastasis

Y Klymenko, O Kim, E Loughran, J Yang, R Lombard… - Oncogene, 2017 - nature.com
During epithelial ovarian cancer (EOC) progression, intraperitoneally disseminating tumor
cells and multicellular aggregates (MCAs) present in ascites fluid adhere to the peritoneum …

[HTML][HTML] Pathophysiology of colorectal peritoneal carcinomatosis: Role of the peritoneum

L Lemoine, P Sugarbaker… - World journal of …, 2016 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third most common cancer and the fourth most common
cause of cancer-related death worldwide. Besides the lymphatic and haematogenous routes …

Selectin-independent adhesion during ovarian cancer metastasis

NA Khaustova, DV Maltseva, L Oliveira-Ferrer… - Biochimie, 2017 - Elsevier
Abstract Purpose Ovarian cancer (OvCa) progression mainly takes place by intraperitoneal
spread. Adhesion of tumor cells to the mesothelial cells which form the inner surface of the …

Early adaptation of colorectal cancer cells to the peritoneal cavity is associated with activation of “stemness” programs and local inflammation

J Barriuso, RT Nagaraju, S Belgamwar… - Clinical Cancer …, 2021 - AACR
Purpose: At diagnosis, colorectal cancer presents with synchronous peritoneal metastasis in
up to 10% of patients. The peritoneum is poorly characterized with respect to its …