The presence of a large variety of more or less specific transport systems in the cytoplasmic
membrane of living cells has long been established. It is generally believed that these …

In 1913 Van Slyke and Meyer made the incisive observation that animal tissues hold a
significant amino acid pool intracellularly and accumulate these compounds from the …

It has become increasingly evident during the last decade that cell membranes are
equipped with factors that play specific roles in conveying both inorganic and organic …

The transport of amino acids across the plasma membranes of mammalian cells is a process
of fundamental physiological importance and has been the object of extensive study. The …

22 HEINZ by Goresky et al.(8) who found that this fits the experimental observa tions. Since
this model implies equal mobility for loaded and unloaded car riers, a revision might be …

Membranes that surround living cells are needed to hold cells together, to keep their
metabolites from diffusing away, and to keep out toxic materials. The membrane constitutes …

One or a few mechanistic principles are assumed to subserve cellular transport of a wide
variety of ions and molecules. Since our present knowl edge of these principles is …

The growth of the field of biological transport is explosive, therefore imн possible to
summarize in a brief review. A preliminary survey of the comн munications published on this …

M'ovement of nutrients (amino acids and sugars) into~ and out of cells is predominantly
mediated by plasma membrane-bound activities that represent the function of discrete …

Kinetic investigations over many years have established that the transport of nutrients into
cells is mediated by specific carriers localized within the cell membrane. In its simplest form …