Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity

M Rios, G Fan, C Fekete, J Kelly, B Bates… - Molecular …, 2001 - academic.oup.com
Brain-derived neurotrophic factor has been associated previously with the regulation of food
intake. To help elucidate the role of this neurotrophin in weight regulation, we have …

Depletion of glial cell line-derived neurotrophic factor in substantia nigra neurons of Parkinson's disease brain

NB Chauhan, GJ Siegel, JM Lee - Journal of chemical neuroanatomy, 2001 - Elsevier
The distribution of nerve growth factor (NGF), ciliary neurotrophic factor (CNTF), glial cell line-
derived neurotrophic factor (GDNF), brain derived neurotrophic factor (BDNF), neurotrophin …

Short-term GDNF treatment provides long-term rescue of lesioned nigral dopaminergic neurons in a rat model of Parkinson's disease

C Winkler, H Sauer, CS Lee… - Journal of …, 1996 - Soc Neuroscience
Glial cell line-derived neurotrophic factor (GDNF) has been shown to exert neuroprotective
effects on dopamine (DA) neurons in vivo. Here we report long-term rescue of nigral DA …

Brain‐derived neurotrophic factor enhances glucose utilization in peripheral tissues of diabetic mice

M Yamanaka, A Tsuchida, T Nakagawa… - Diabetes, Obesity …, 2007 - Wiley Online Library
Aims: Repetitive subcutaneous or intracerebroventricular administration of brain‐derived
neurotrophic factor (BDNF) ameliorates glucose metabolism and enhances energy …

Acute effects of brain-derived neurotrophic factor on energy expenditure in obese diabetic mice

A Tsuchida, T Nonomura, M Ono-Kishino… - International journal of …, 2001 - nature.com
OBJECTIVE: We recently demonstrated that chronic treatment with brain-derived
neurotrophic factor (BDNF) regulates energy expenditure in obese diabetic C57BL/KsJ …

Neuroprotective signaling and the aging brain: take away my food and let me run

MP Mattson - Brain research, 2000 - Elsevier
It is remarkable that neurons are able to survive and function for a century or more in many
persons that age successfully. A better understanding of the molecular signaling …

Dietary restriction retards the age-associated loss of rat striatal dopaminergic receptors

P Levin, JK Janda, JA Joseph, DK Ingram, GS Roth - Science, 1981 - science.org
In male Wistar rats subjected to dietary restriction by alternate days of feeding and fasting
the normal age-associated loss of striatal dopamine receptors in the brain was substantially …

[HTML][HTML] Malnutrition and reactivity to drugs acting in the central nervous system

SOS Almeida, J Tonkiss, JR Galler - Neuroscience & Biobehavioral …, 1996 - Elsevier
ALMEIDA, SS; J. TONKISS AND JR GALLER. Malnutrition and reactivity to drugs acting in
the central nervous system. NEUROSCI BIOBEHAV REV 20 (3) 389–402, 1996.—There is a …

Human neural progenitors deliver glial cell line-derived neurotrophic factor to parkinsonian rodents and aged primates

S Behrstock, A Ebert, J McHugh, S Vosberg, J Moore… - Gene therapy, 2006 - nature.com
Glial cell line-derived neurotrophic factor (GDNF) has been shown to increase the survival
and functioning of dopamine neurons in a variety of animal models and some recent human …

Role of exercise‐induced brain‐derived neurotrophic factor production in the regulation of energy homeostasis in mammals

BK Pedersen, M Pedersen, KS Krabbe… - Experimental …, 2009 - Wiley Online Library
Brain‐derived neurotrophic factor (BDNF) has been shown to regulate neuronal
development and plasticity and plays a role in learning and memory. Moreover, it is well …