[HTML][HTML] CircRNAs open a new era in the study of cardiovascular disease

Z Yu, Q Huang, Q Zhang, H Wu… - … Journal of Molecular …, 2021 - spandidos-publications.com
Circular RNAs (circRNAs) are non‑coding RNAs that are found in the cytoplasm or stored in
the exosomes, where they are not affected by RNA exonucleases. CircRNAs are widely …

Circular RNAs: functions and clinical significance in cardiovascular disease

L Zhang, Y Zhang, Y Wang, Y Zhao… - Frontiers in cell and …, 2020 - frontiersin.org
Cardiovascular disease (CVD) causes high morbidity and mortality worldwide. Accumulating
research has indicated the possible roles played by circular RNAs (circRNAs) in the …

Circular RNAs as novel biomarkers for cardiovascular diseases

Q Zhou, Z Zhang, Y Bei, G Li, T Wang - Circular RNAs: Biogenesis and …, 2018 - Springer
Cardiovascular diseases are among the most serious diseases, which are a leading cause
of death across the world. Early diagnosis and prognosis prediction are keys for treatment …

Circular RNA in cardiovascular disease: Expression, mechanisms and clinical prospects

Y Tang, J Bao, J Hu, L Liu, DY Xu - Journal of cellular and …, 2021 - Wiley Online Library
Circular RNAs (circRNAs) are a group of covalently closed, endogenous, non‐coding RNAs,
which exist widely in human tissues including the heart. Increasing evidence has shown that …

The emerging landscape of circular RNA in cardiovascular diseases

M Zhou, JM Yang, X Xiong - Journal of Molecular and Cellular Cardiology, 2018 - Elsevier
Circular RNAs (circRNAs), a large novel type of endogenous transcripts, have become a
new research hotspot in the field of RNA biology. CircRNAs are mainly generated from …

The function and therapeutic potential of circular RNA in cardiovascular diseases

K Wang, XQ Gao, T Wang, LY Zhou - Cardiovascular Drugs and Therapy, 2021 - Springer
Circular RNA (circRNA) has a closed-loop structure, and its 3'and 5'ends are directly
covalently connected by reverse splicing, which is more stable than linear RNA. CircRNAs …

Circular noncoding RNAs as potential therapies and circulating biomarkers for cardiovascular diseases

AS Bayoumi, T Aonuma, J Teoh, Y Tang… - Acta Pharmacologica …, 2018 - nature.com
Recent advancements in genome-wide analyses and RNA-sequencing technologies led to
the discovery of small noncoding RNAs, such as microRNAs (miRs), as well as both linear …

[HTML][HTML] A narrative review of circular RNAs as potential biomarkers and therapeutic targets for cardiovascular diseases

C Liu, N Li, G Dai, O Cavdar, H Fang - Annals of Translational …, 2021 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs), a novel class of non-coding RNA, are produced by back-splicing
and were initially considered to be by-products of splicing. In recent years, computational …

A novel strategy of identifying circRNA biomarkers in cardiovascular disease by meta‐analysis

JJH Li, W Wang, XQ Wang, Y He… - Journal of cellular …, 2019 - Wiley Online Library
Circular RNAs (circRNAs) are stable and abundantly expressed in vivo but are abnormally
expressed in several diseases. This study aimed to identify circRNAs acting as potential …

[HTML][HTML] Circular RNAs as a promising biomarker for heart disease

YK Kim - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Heart-related diseases account for a high proportion of deadly pathologies, so a large
number of studies have been conducted to discover potential biomarkers for the early …