[HTML][HTML] SARS-CoV-2 cell entry and targeted antiviral development

Z Chen, R Du, JMG Achi, L Rong, Q Cui - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the pandemic coronavirus disease 2019 (COVID-19), which threatens human health and …

SARS‐CoV‐2 spike protein enhances MAP4K3/GLK‐induced ACE2 stability in COVID‐19

HC Chuang, CH Hsueh, PM Hsu… - EMBO Molecular …, 2022 - embopress.org
ACE2 on epithelial cells is the SARS‐CoV‐2 entry receptor. Single‐cell RNA‐sequencing
data derived from two COVID‐19 cohorts revealed that MAP4K3/GLK‐positive epithelial …

[HTML][HTML] Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system

ML Yeung, JLL Teng, L Jia, C Zhang, C Huang, JP Cai… - Cell, 2021 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause acute
respiratory disease and multiorgan failure. Finding human host factors that are essential for …

[HTML][HTML] Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2

L El-Shennawy, AD Hoffmann, NK Dashzeveg… - Nature …, 2022 - nature.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the
pandemic of the coronavirus induced disease 2019 (COVID-19) with evolving variants of …

[HTML][HTML] SARS-CoV-2 infects cells after viral entry via clathrin-mediated endocytosis

A Bayati, R Kumar, V Francis, PS McPherson - Journal of Biological …, 2021 - ASBMB
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
COVID-19, so understanding its biology and infection mechanisms is critical to facing this …

[HTML][HTML] Computational and experimental studies reveal that thymoquinone blocks the entry of coronaviruses into in vitro cells

H Xu, B Liu, Z Xiao, M Zhou, L Ge, F Jia, Y Liu… - Infectious diseases and …, 2021 - Springer
Abstract Introduction Since December 2019, severe acute respiratory syndrome-related
coronavirus-2 (SARS-CoV-2) has caused the coronavirus disease 2019 (COVID-19) …

SARS-CoV-2 entry in host cells-multiple targets for treatment and prevention

IS Mahmoud, YB Jarrar, W Alshaer, S Ismail - Biochimie, 2020 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new viral disease that
has gained global attention owing to its ability to provoke community and health-care …

[HTML][HTML] SARS-CoV-2 S glycoprotein binding to multiple host receptors enables cell entry and infection

I Trbojević-Akmačić, T Petrović, G Lauc - Glycoconjugate journal, 2021 - Springer
The severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) infection
displays a wide array of clinical manifestations. Although some risk factors for coronavirus …

[HTML][HTML] 1, 2, 3, 4, 6-Pentagalloyl glucose, a RBD-ACE2 binding inhibitor to prevent SARS-CoV-2 infection

RH Chen, LJ Yang, S Hamdoun, SK Chung… - Frontiers in …, 2021 - frontiersin.org
The outbreak of SARS-CoV-2 virus caused more than 80,155,187 confirmed COVID-19
cases worldwide, which has posed a serious threat to global public health and the economy …

[HTML][HTML] Ceftazidime is a potential drug to inhibit SARS-CoV-2 infection in vitro by blocking spike protein–ACE2 interaction

CD Lin, Y Li, YB Zhang, ZY Liu, X Mu, C Gu… - Signal transduction and …, 2021 - nature.com
Coronavirus disease 2019 (COVID-19) has spread globally as a severe pandemic, which is
caused by a novel coronavirus named Severe Acute Respiratory Syndrome coronavirus 2 …