Galanin plasticity in the cholinergic basal forebrain in Alzheimer's disease and transgenic mice

EJ Mufson, SE Counts, SE Perez, L Binder - Neuropeptides, 2005 - Elsevier
Galanin (GAL) is a biologically active 29 amino acid (30 in humans) which participates in the
modulation of several ascending neurotransmitter systems including cholinergic basal …

Galanin: neurobiologic mechanisms and therapeutic potential for Alzheimer's disease

SE Counts, SE Perez, U Kahl, T Bartfai… - CNS Drug …, 2001 - Wiley Online Library
The neuropeptide galanin (GAL) is widely distributed in the mammalian CNS. Several lines
of evidence suggest that GAL may play a critical role in cognitive processes such as memory …

Galanin–25 years with a multitalented neuropeptide: Galanin in Alzheimer's disease: Neuroinhibitory or neuroprotective?

SE Counts, SE Perez, EJ Mufson - Cellular and Molecular Life Sciences, 2008 - Springer
Galanin (GAL) and GAL receptors (GALRs) are overexpressed in degenerating brain
regions associated with cognitive decline in Alzheimer's disease (AD). The functional …

Neuroprotective role for galanin in Alzheimer's disease

SE Counts, SE Perez, SD Ginsberg, EJ Mufson - Galanin, 2010 - Springer
Galanin (GAL) and GAL receptors (GALR) are overexpressed in degenerating brain regions
associated with cognitive decline in Alzheimer's disease (AD). The functional consequences …

[HTML][HTML] Galanin in Alzheimer disease

SE Counts, SE Perez, SD Ginsberg… - Molecular …, 2003 - triggered.edina.clockss.org
Galanin (GAL) and GAL receptors (GALR) are overexpressed in limbic brain regions
associated with cognition in Alzheimer disease (AD). The functional consequences of this …

Galanin fiber hypertrophy within the cholinergic nucleus basalis during the progression of Alzheimer's disease

SE Counts, EY Chen, S Che, MD Ikonomovic… - Dementia and geriatric …, 2006 - karger.com
Galanin (GAL)-containing fibers enlarge and hyperinnervate remaining cholinergic basal
forebrain (CBF) neurons within the anterior nucleus basalis (NB) in late-stage Alzheimer's …

Galanin hyperinnervation upregulates choline acetyltransferase expression in cholinergic basal forebrain neurons in Alzheimer's disease

SE Counts, B He, S Che, SD Ginsberg… - Neurodegenerative …, 2008 - karger.com
Background: Fibers containing galanin (GAL) enlarge and hyperinnervate cholinergic basal
forebrain (CBF) nucleus basalis (NB) neurons in late-stage Alzheimer's disease (AD), yet the …

Galanin fiber hyperinnervation preserves neuroprotective gene expression in cholinergic basal forebrain neurons in Alzheimer's disease

SE Counts, B He, S Che, SD Ginsberg… - Journal of Alzheimer's …, 2009 - content.iospress.com
Fibers containing galanin (GAL) hyperinnervate cholinergic basal forebrain (CBF) nucleus
basalis neurons in late stage Alzheimer's disease (AD), yet the molecular consequences of …

Local cholinergic-GABAergic circuitry within the basal forebrain is modulated by galanin

JC Damborsky, KG Smith, P Jensen… - Brain Structure and …, 2017 - Springer
The basal forebrain (BF) is an important regulator of hippocampal and cortical activity. In
Alzheimer's disease (AD), there is a significant loss and dysfunction of cholinergic neurons …

Long-term plastic changes in galanin innervation in the rat basal forebrain

I Hartonian, EJ Mufson, S De Lacalle - Neuroscience, 2002 - Elsevier
Galanin immunoreactive fibers hyperinnervate remaining cholinergic basal forebrain
neurons in Alzheimer's disease, perhaps exacerbating the cholinergic deficit. The purpose …