Pulmonary fibrotic diseases are characterized by proliferation of lung fibroblasts and
myofibroblasts and excessive deposition of extracellular matrix proteins. Depending on the …

Inflammation is an essential mechanism of various diseases. The development and
resolution of inflammation are complex immune-modulation processes which induce the …

Idiopathic pulmonary fibrosis (IPF) is the representative phenotype of interstitial lung disease
where severe scarring develops in the lung interstitium. Although antifibrotic treatments are …

Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease of unknown etiology
characterized by distorted distal lung architecture, inflammation, and fibrosis. The molecular …

Fibrogenesis involves a dynamic interplay between factors that promote the biosynthesis
and deposition of extracellular matrix along with pathways that degrade the extracellular …

Exposure to air pollution and other environmental inhalation hazards, such as occupational
exposures to dusts and fumes, aeroallergens, and tobacco smoke, is a significant cause of …

The mechanisms of pulmonary fibrosis are complex, and several hypotheses have been put
forward to explain how fibrosis develops. It was long thought that inflammation was a key …

Introduction: Fibrosis is an irreversible pathological endpoint in many chronic diseases,
including pulmonary fibrosis. Idiopathic pulmonary fibrosis (IPF) is a progressive and often …

The pathogenesis idiopathic pulmonary of fibrosis and related fibrosis lung disorders are
complex and poorly understood. This likely involves cellular mechanisms that result in loss …

Idiopathic pulmonary fibrosis (IPF) is characterized by progressive extracellular matrix
deposition in the lung parenchyma leading to the destruction of lung structure, respiratory …