Achieving intracellular delivery of protein therapeutics within cells remains a significant
challenge. Although custom formulations are available for some protein therapeutics, the …

Biodegradable “scaffold” polyphosphazenes were investigated as carriers for a single-step
non-covalent PEGylation of proteins. These water-soluble polymers include poly (ethylene …

A series of biodegradable drug delivery polymers with intrinsic multifunctionality have been
designed and synthesized utilizing a polyphosphazene macromolecular engineering …

Polyphosphazenes have been exploited as carriers for protein delivery due to versatility of
molecular structures and sophisticated spectrum of chemical and physical properties. Ease …

Studies on the biological performance of nanomedicines have been increasingly focused on
the paradigm shifting role of the protein corona, which is imminently formed once the …

This study involved the construction of self-assembled nanoparticles from novel pH-sensitive
amphiphilic polyphosphazenes. These nanoparticles provide fast pH-responsive drug …

Water-soluble polyphosphazene polyacids, such as poly [di (carboxylatophenoxy)
phosphazene](PCPP), have been of significant interest due to their unique immunoadjuvant …

Polyphosphazenes bearing cationic moieties were synthesized from poly (dichloro)
phosphazene, which in turn was obtained by thermal polymerization of …

Using a living cationic polymerisation procedure we synthesised a series of multi-armed
poly (organo) phosphazenes with controlled molecular weights and excellent aqueous …

Novel oppositely charged polyphosphazene polyelectrolytes containing grafted poly
(ethylene glycol)(PEG) chains were synthesized as modular components for the assembly of …