Angelman syndrome (AS) is a rare genetic neurodevelopmental disorder with profoundly
debilitating symptoms with no FDA-approved cure or therapeutic. Brain-derived neurotrophic …

Angelman Syndrome (AS) is a severe cognitive disorder caused by loss of neuronal
expression of the E3 ubiquitin ligase UBE3A. In an AS mouse model, we previously reported …

Angelman syndrome (AS) is a neurodevelopment disorder characterized by severe
cognitive impairment and a high rate of autism. AS is caused by disrupted neuronal …

Neurodevelopmental disorders (NDDs) are often linked to disruption in brain development
and present challenges for affected individuals in achieving their cognitive, emotional, and …

Angelman syndrome is characterised by cognitive impairment with profound speech delay,
motor impairments and ataxic-like symptoms, EEG abnormalities and drug-resistant …

Angelman syndrome (AS) is a severe neurodevelopmental disorder associated with
disruption of maternally inherited UBE3A (ubiquitin protein ligase E3A) expression. At the …

Angelman syndrome (AS) is a severe neurodevelopmental disorder caused by the loss of
neuronal E3 ligase UBE3A with no available treatment. Restoring UBE3A levels via …

Angelman syndrome is a rare neurodevelopmental disorder caused by a mutation in the
maternal allele of the gene Ube3a. The primary symptoms of Angelman syndrome are …

Angelman syndrome (AS) is a single-gene neurodevelopmental disorder associated with
cognitive and motor impairment, seizures, lack of speech, and disrupted sleep. AS is caused …

Angelman syndrome (AS) is a severe neurodevelopmental disorder for which only
symptomatic treatment with limited benefits is available. AS is caused by mutations affecting …