Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐
related quality of life and poor functional status. However, there is limited guidance on …

Abstract Purpose of Review The treatment of pain in patients with cirrhosis is complicated by
unpredictable hepatic drug metabolism and a higher risk of adverse drug reactions. We …

Background: Chronic pain is common in cirrhosis; however, the mechanistic classifications
are not well characterized. Nociplastic pain, for instance, is associated with comorbid …

Management of pain in this population is complex due to patient, clinician, pharmacological,
and regulatory factors (Fig. 1). Bias, fear of litigation, and impaired metabolism/excretion …

Pain management in patients with liver cirrhosis is a real challenge and is often inadequate
due to a lack of therapeutic efficacy or the high incidence of adverse effects. The focus of …

Pain management in patients with cirrhosis is a difficult clinical challenge for health care
professionals, and few prospective studies have offered an evidence-based approach. In …

Purpose of the review Though it is well known that cirrhosis is associated with significant
morbidity and mortality, management of symptoms in cirrhosis can be difficult. This review …

JH Pain is very common in patients with liver disease, much like it is in the general
population. Patients with liver disease can have pain that any person may have (eg, chronic …

Background & Aims Cirrhosis is associated with significant pain and disability, the etiologies
of which are poorly understood. We investigated whether the pain and disability in patients …

Background Pain is common in patients with liver disease, difficult to treat, and poorly
understood. Aims The aim of this study was to determine factors associated with pain and …