Osteopontin (OPN) is a key immunoregulator in the autoimmune-mediated demyelinating
disease multiple sclerosis. OPN may also play a role in the remyelination since it is 1) a …

Osteopontin (OPN) is known to be significantly involved in the pathogenesis of rheumatoid
arthritis (RA). This study aimed to evaluate if the serum concentration of OPN in patients with …

Osteopontin is a proinflammatory molecule, modulating TH1 and TH17 responses. Several
reports suggest its involvement in multiple sclerosis (MS) pathogenesis. We previously …

Background. Osteopontin (OPN) is an extracellular matrix cell adhesion phosphoprotein with
immunological activities including stimulation of macrophage chemotaxis, T-helper type 1 …

Background Osteopontin (OPN) plays a key role in the progression of TH 1-immune-
mediated disease in models of multiple sclerosis and rheumatoid arthritis. Aim To determine …

Background After an acute ischaemic stroke (AIS), several inflammatory biomarkers have
been investigated, but their predictive role on functional recovery remains to be validated …

Objectives. To determine whether osteopontin (OPN) is increased in patients with AS and to
investigate its relationship to inflammatory disease activity and bone remodelling process …

The whole protein of osteopontin (OPN full) and its cleaved form (OPN N-half) are involved
in the immune response and the migration of immune cells to an inflammatory lesion. We …

Osteopontin (OPN) was shown to be involved in inflammatory and degenerative processes
of the nervous system. In multiple sclerosis, the role of OPN has been studied in the …

Osteopontin (Opn) is a broadly expressed pleiotropic cytokine, and has been shown to play
an important role in various autoimmune diseases, including multiple sclerosis (MS) and its …