A role for osteopontin (OPN) in promoting disease activity of multiple sclerosis or its animal
model experimental autoimmune encephalomyelitis (EAE) has recently been suggested. As …

Aim To assess whether any form of osteopontin (OPN) is correlated with bone resorption
markers or treatment effects in rheumatoid arthritis (RA). Method Subjects comprised 119 …

The human brain is populated by perivascular T cells with a tissue-resident memory T (T
RM)-cell phenotype, which in multiple sclerosis (MS) associate with lesions. We investigated …

Multiple sclerosis is a demyelinating disease, characterized by inflammation in the brain and
spinal cord, possibly due to autoimmunity. Large-scale sequencing of cDNA libraries …

The proinflammatory cytokine osteopontin (OPN) is elevated in the cerebrospinal fluid (CSF)
in individuals with HIV-associated neurocognitive disorders (HAND) and remains so in those …

1 Department of Health. Copying letters to patients: good practice guidelines. London:
Department of Health, 2003. http://www. dh. gov. uk/dr_consum_dh/groups/dh_digital …

Introduction Osteopontin (OPN) has been implicated as a mediator of Th17 regulation via
type I interferon (IFN) receptor signaling and in macrophage activity at sites of tissue repair …

Osteopontin (OPN) is a multifunctional cytokine and adhesion molecule, as well as an
unusual regulator for both innate and adaptive immune responses. Several immune cells …

Recent research has led to a better but as yet incomplete understanding of the complex
roles osteopontin plays in mammalian physiology. A soluble protein found in all body fluids …

Osteopontin (OPN) is a matricellular protein with proinflammatory and profibrotic properties.
Previous reports demonstrate a role for OPN in wound healing and pulmonary fibrosis. Here …