Background and aims Osteopontin is implicated in atherosclerosis, and its expression is
upregulated in response to brain injury. The aim of this study was to prospectively …

Background and Objectives To evaluate the extent of intrathecal inflammation in patients
with primary progressive MS (PPMS) at the time of diagnosis and to define markers and a …

We have used in vitro oligodendrocyte differentiation and the in vivo remyelination model,
the cuprizone model, to identify genes regulating oligodendrocyte function and …

We analyzed expression of osteopontin (OPN), a cytokine regulating tissue repair and
inflammation, in astrocytes and microglia in response to systemic lipopolysaccharide (LPS) …

Osteopontin (OPN) is a proinflammatory cytokine that can be secreted from many cells,
including activated macrophages and T‐lymphocytes, and is widely distributed in many …

Osteopontin (OPN) is an adhesive glycoprotein linked to a variety of pathophysiological
processes. We investigated whether OPN might act as an opsonin in the diseased brain by …

Osteopontin (OPN), an extracellular matrix (ECM) glyco-phosphoprotein, plays an important
role in autoimmune-mediated demyelinating diseases, including multiple sclerosis and …

Elevated serum levels of osteopontin have been associated with cardiovascular disease,
diabetic nephropathy, and autoimmune disease activity. Aim of the study was to investigate …

Objective. To measure concentrations of the thrombin-cleaved isoform of osteopontin (OPN)
in urine and plasma of patients with rheumatoid arthritis (RA), and to assess whether levels …

Osteopontin (OPN), also known as early T-cell activating gene (Eta-1), has been recently
shown to be a critical factor in the progression of experimental autoimmune …