Eur J Clin Invest 2010; 40 (4): 294–300 Abstract Background The pleiotropic cytokine
osteopontin (OPN) is thought to be involved in the pathogenesis of atherosclerosis …

Osteopontin (OPN) is a secreted glycophosphoprotein that has a role in inflammation,
immune response and calcification. We hypothesized that plasma OPN levels are …

Osteopontin (OPN) regulates the immune response at multiple levels. Physiologically, it
regulates the host response to infections by driving T helper (Th) polarization and acting on …

Osteopontin (OPN) is an extracellular matrix protein of pleiotropic properties and has been
recently recognized as a potential inflammatory cytokine. In this study, we demonstrate, for …

In this study, we examined osteopontin (OPN) production in myeloma cells and plasma OPN
levels in multiple myeloma (MM) patients. We assessed OPN production in bone marrow …

The joint disease osteoarthritis (OA) is the most common form of arthritis, which mainly
affects the older people. OA is becoming one of the major non-fatal health burdens of the …

Circulating full-length osteopontin (FL-OPN) is elevated in plasma from patients with various
infectious diseases, such as adult T-cell leukemia, Mycobacterium tuberculosis (TB) …

Objectives: To develop an immunoassay for osteopontin (OPN), a secreted
phosphoglycoprotein that is implicated in a number of human diseases, and establish basal …

Osteopontin (OPN) is a multifunctional molecule highly expressed in chronic inflammatory
and autoimmune diseases, and it is specifically localized in and around inflammatory cells …

OBJECTIVES: Osteopontin (OPN) is associated with several human malignancies, but the
role of OPN in head and neck cancer (HNC) remains unclear. We investigated the …