Osteopontin: a multifunctional molecule regulating chronic inflammation and vascular disease
M Scatena, L Liaw, CM Giachelli - Arteriosclerosis, thrombosis, and …, 2007 - Am Heart Assoc
Osteopontin (OPN) is a multifunctional molecule highly expressed in chronic inflammatory
and autoimmune diseases, and it is specifically localized in and around inflammatory cells …
and autoimmune diseases, and it is specifically localized in and around inflammatory cells …
Quantification of osteopontin in human plasma with an ELISA: basal levels in pre-and postmenopausal women
DS Bautista, Z Saad, AF Chambers, KS Tonkin… - Clinical …, 1996 - Elsevier
Objectives: To develop an immunoassay for osteopontin (OPN), a secreted
phosphoglycoprotein that is implicated in a number of human diseases, and establish basal …
phosphoglycoprotein that is implicated in a number of human diseases, and establish basal …
Both full-length and protease-cleaved products of osteopontin are elevated in infectious diseases
T Hattori, H Iwasaki-Hozumi, G Bai, H Chagan-Yasutan… - Biomedicines, 2021 - mdpi.com
Circulating full-length osteopontin (FL-OPN) is elevated in plasma from patients with various
infectious diseases, such as adult T-cell leukemia, Mycobacterium tuberculosis (TB) …
infectious diseases, such as adult T-cell leukemia, Mycobacterium tuberculosis (TB) …
Association of osteopontin with osteoarthritis
C Cheng, S Gao, G Lei - Rheumatology international, 2014 - Springer
The joint disease osteoarthritis (OA) is the most common form of arthritis, which mainly
affects the older people. OA is becoming one of the major non-fatal health burdens of the …
affects the older people. OA is becoming one of the major non-fatal health burdens of the …
Clinical significance of elevated osteopontin levels in head and neck cancer patients
M Eto, S Kodama, N Nomi, N Uemura, M Suzuki - Auris Nasus Larynx, 2007 - Elsevier
OBJECTIVES: Osteopontin (OPN) is associated with several human malignancies, but the
role of OPN in head and neck cancer (HNC) remains unclear. We investigated the …
role of OPN in head and neck cancer (HNC) remains unclear. We investigated the …
Association of osteopontin with ischemic axonal death in periventricular leukomalacia
F Tanaka, Y Ozawa, Y Inage, K Deguchi, M Itoh… - Acta …, 2000 - Springer
Osteopontin (OPN) is a bone matrix protein expressed my macrophages and related to the
process of tissue calcification, and is also known to protect ischemic cells. To understand …
process of tissue calcification, and is also known to protect ischemic cells. To understand …
CSF inflammation and axonal damage are increased and correlate in progressive multiple sclerosis
J Romme Christensen, L Börnsen… - Multiple Sclerosis …, 2013 - journals.sagepub.com
Background: The mechanism underlying disease progression in progressive multiple
sclerosis (MS) is uncertain. Pathological studies found widespread inflammation in …
sclerosis (MS) is uncertain. Pathological studies found widespread inflammation in …
OPN polymorphism is associated with the susceptibility to cervical spondylotic myelopathy and its outcome after anterior cervical corpectomy and fusion
J Wu, D Wu, K Guo, F Yuan, B Ran - Cellular Physiology and …, 2014 - karger.com
Background: Osteopontin (OPN) is reportedly involved in bone desorption, formation and
ectopic calcification. We sought to investigate the role of OPN gene polymorphism in the …
ectopic calcification. We sought to investigate the role of OPN gene polymorphism in the …
The value of osteopontin in the assessment of bone mineral density status in postmenopausal women
Background Osteopontin (OPN) has been implicated in bone remodeling by activating the
resorption process. We aimed to study the relationship between OPN, bone mineral density …
resorption process. We aimed to study the relationship between OPN, bone mineral density …
Elevated serum levels of osteopontin in HCV-associated lymphoproliferative disorders
M Libra, M Indelicato, V De Re, AL Zignego… - Cancer biology & …, 2005 - Taylor & Francis
Hepatitis C virus (HCV) infection is associated with chronic hepatitis, cirrhosis, and
hepatocellular carcinoma. Recent evidences have also suggested that HCV infection …
hepatocellular carcinoma. Recent evidences have also suggested that HCV infection …