Role of osteopontin in induction of monocyte chemoattractant protein 1 and macrophage inflammatory protein 1β through the NF‐κB and MAPK pathways in …
W Zheng, R Li, H Pan, D He, R Xu… - … : Official Journal of …, 2009 - Wiley Online Library
Objective Osteopontin (OPN) is a proinflammatory protein with a critical role in leukocyte
migration. Although OPN has been implicated in rheumatoid arthritis (RA), its underlying …
migration. Although OPN has been implicated in rheumatoid arthritis (RA), its underlying …
Osteopontin/secreted phosphoprotein‐1 harnesses glial‐, immune‐, and neuronal cell ligand‐receptor interactions to sense and regulate acute and chronic …
A Yim, C Smith, AM Brown - Immunological reviews, 2022 - Wiley Online Library
Osteopontin (OPN) also known by its official gene designation secreted phosphoprotein‐1
(SPP1) is a fascinating, multifunctional protein expressed in a number of cell types that …
(SPP1) is a fascinating, multifunctional protein expressed in a number of cell types that …
Serum osteopontin levels in relation to bone mineral density and bone turnover markers in postmenopausal women
Q Wei, L Huang, X Tan, Z Chen, S Chen… - … Journal of Clinical and …, 2016 - Taylor & Francis
Osteopontin (OPN) is an extracellular matrix protein that is expressed in bone cells such as
osteoblast and osteocytes and associated with bone turnover and bone mineral density …
osteoblast and osteocytes and associated with bone turnover and bone mineral density …
Plasma osteopontin may predict neuroinflammation and the severity of pediatric traumatic brain injury
N Gao, X Zhang-Brotzge, B Wali… - Journal of Cerebral …, 2020 - journals.sagepub.com
Traumatic brain injury (TBI) is the leading cause of death in children and adolescents in
developed countries, but there are no blood-based biomarkers to support the diagnosis or …
developed countries, but there are no blood-based biomarkers to support the diagnosis or …
The immunohistochemical expression profile of osteopontin in normal human tissues using two site-specific antibodies reveals a wide distribution of positive cells and …
Y Kunii, S Niwa, Y Hagiwara, M Maeda… - Medical molecular …, 2009 - Springer
To elucidate the cellular distribution of osteopontin (OPN) in normal human tissues, we
undertook immunohistochemistry using two site-specific OPN antibodies. The 10A16 …
undertook immunohistochemistry using two site-specific OPN antibodies. The 10A16 …
Overexpression of osteopontin in rheumatoid synovial mononuclear cells is associated with joint inflammation, not with genetic polymorphism.
G Xu, W Sun, D He, L Wang, W Zheng, H Nie… - The Journal of …, 2005 - jrheum.org
OBJECTIVE: Osteopontin (OPN) is thought to play an important role in rheumatoid synovitis.
We investigated the expression of OPN in rheumatoid synovial fluid mononuclear cells …
We investigated the expression of OPN in rheumatoid synovial fluid mononuclear cells …
Increased osteopontin expression following intranigral lipopolysaccharide injection in the rat
J Iczkiewicz, S Rose, P Jenner - European Journal of …, 2005 - Wiley Online Library
Nigral cell death in Parkinson's disease is characterized by glial cell activation leading to
inflammatory changes. Osteopontin (OPN) is a glycosylated phosphoprotein that is induced …
inflammatory changes. Osteopontin (OPN) is a glycosylated phosphoprotein that is induced …
Osteopontin: a new emerging role in psoriasis
E Buommino, MA Tufano, N Balato, N Canozo… - Archives of …, 2009 - Springer
Osteopontin (OPN) is a phosphorylated acidic glycoprotein produced by cells of the immune
system, epithelial tissue, smooth muscle cells, osteoblasts, and tumor cells. OPN interacts …
system, epithelial tissue, smooth muscle cells, osteoblasts, and tumor cells. OPN interacts …
Intracellular osteopontin (iOPN) and immunity
M Inoue, ML Shinohara - Immunologic research, 2011 - Springer
Osteopontin (OPN) is a protein involved in various pathophysiological events. OPN has
been studied as a secreted protein, but recent reports showed that OPN can be found in the …
been studied as a secreted protein, but recent reports showed that OPN can be found in the …
Osteopontin, a multi-faceted molecule
D Chabas - Medecine Sciences: M/S, 2005 - europepmc.org
Osteopontin (OPN) was initially isolated from bovine bone cortex, as a complex syalilated
phospho-glyco-protein of around 60 kDa, with many postranslational modifications. It has …
phospho-glyco-protein of around 60 kDa, with many postranslational modifications. It has …