Lobar evenness of deposition/retention in rat lungs of inhaled silver nanoparticles: an approach for reducing animal use while maximizing endpoints

JD Park, JK Kim, MS Jo, YH Kim, KS Jeon… - Particle and Fibre …, 2019 - Springer
Background Information on particle deposition, retention and clearance are important for the
evaluation of the risk of inhaled nanomaterials to human health. Recent revised OECD …

Even lobar deposition of poorly soluble gold nanoparticles (AuNPs) is similar to that of soluble silver nanoparticles (AgNPs)

HP Kim, JK Kim, MS Jo, JD Park, K Ahn… - Particle and Fibre …, 2020 - Springer
Background Information on particle deposition, retention, and clearance is important when
evaluating the risk of inhaled nanomaterials to human health. The revised Organization …

Mode of silver clearance following 28-day inhalation exposure to silver nanoparticles determined from lung burden assessment including post-exposure observation …

MS Jo, JK Kim, Y Kim, HP Kim, HS Kim, K Ahn… - Archives of …, 2020 - Springer
Recently revised OECD inhalation toxicity testing guidelines require measurements of lung
burden immediately after and for periods following exposure for nanomaterials. Lung burden …

Influence of particle size on persistence and clearance of aerosolized silver nanoparticles in the rat lung

DS Anderson, ES Patchin, RM Silva… - Toxicological …, 2015 - academic.oup.com
The growing use of silver nanoparticles (AgNPs) in consumer products raises concerns
about potential health effects. This study investigated the persistence and clearance of 2 …

Particle size dependent deposition and pulmonary inflammation after short-term inhalation of silver nanoparticles

HM Braakhuis, I Gosens, P Krystek, JAF Boere… - Particle and fibre …, 2014 - Springer
Background Although silver nanoparticles are currently used in more than 400 consumer
products, it is not clear to what extent they induce adverse effects after inhalation during …

Remote effects and biodistribution of pulmonary instilled silver nanoparticles in mice

Z Ferdous, S Al-Salam, P Yuvaraju, BH Ali, A Nemmar - NanoImpact, 2021 - Elsevier
Silver nanoparticles (AgNPs) are the most commonly used nanoparticles (NPs) owing to
their anti-microbial properties, and the pulmonary system provides a major portal of entry for …

Persistence of silver nanoparticles in the rat lung: Influence of dose, size, and chemical composition

DS Anderson, RM Silva, D Lee, PC Edwards… - …, 2015 - Taylor & Francis
Increasing silver nanoparticle (AgNP) use in sprays, consumer products, and medical
devices has raised concerns about potential health effects. While previous studies have …

Aerosolized silver nanoparticles in the rat lung and pulmonary responses over time

RM Silva, DS Anderson, J Peake… - Toxicologic …, 2016 - journals.sagepub.com
Silver nanoparticle (Ag NP) production methods are being developed and refined to
produce more uniform Ag NPs through chemical reactions involving silver salt solutions …

Pulmonary effects of silver nanoparticle size, coating, and dose over time upon intratracheal instillation

RM Silva, DS Anderson, LM Franzi… - Toxicological …, 2015 - academic.oup.com
Abstract Silver nanoparticles (Ag NPs) can be found in myriad consumer products, medical
equipment/supplies, and public spaces. However, questions remain regarding the risks …

Translating nanoparticle dosimetry from conventional in vitro systems to occupational inhalation exposures

JN Smith, AW Skinner - Journal of aerosol science, 2021 - Elsevier
Abstract As encouraged by Toxicity Testing in the 21st Century, researchers increasingly
apply high-throughput in vitro approaches to identify and characterize nanoparticle hazards …