Acute kidney injury (AKI) is a clinical syndrome that results in severe tubular damage with
high morbidity and mortality. However, there is a lack of effective therapy strategies …

Background Xylitol has antiadhesive effects on Streptococcus pneumoniae and inhibits its
growth, and has also been found to be effective in preventing acute otitis media and has …

Sepsis is an inflammatory disease characterized by dysregulation of inflammation.
Macrophage-mediated inflammation has been implicated in the pathophysiology of sepsis …

Background Sepsis has high morbidity and mortality. The aim of this study was to investigate
whether emodin, an anthraquinone derived from Chinese herb, exerts protective effects on …

Recent reports have shown that antibiotics such as macrolide, aminoglycoside, and
tetracyclines have immunomodulatory effects in addition to essential antibiotic effects. These …

Different antibiotic treatments may affect the survival and physiological responses of Balb/c
mice following cecal ligation and puncture (CLP). The broad spectrum imipenem (IMP) was …

Aims The incidence of secondary systemic fungal infections has sharply increased in
bacterial septic patients. Antimycotics exhibit immunomodulatory properties, yet these effects …

The etiology of inflammatory disorders involves many cellular, plasmatic and humoral
pathways of signaling culminating in the production of enzymatic and free radical mediated …

Acute lung injury (ALI) during sepsis is characterized by bilateral alveolar infiltrates, lung
edema and respiratory failure. Here, we examined the efficacy the DNA methyl transferase …

Gram-negative sepsis resulting in endotoxin triggered septic shock is one of the leading
causes of death in critically ill patients. Because treatment options are limited, recent …