Electrophysiology of 5-HT6 receptors
Publisher Summary A large number of serotonin (5-HT) receptors have been identified over
the past several years. They are currently divided into seven classes (5-HT 1 to 5-HT 7) …
the past several years. They are currently divided into seven classes (5-HT 1 to 5-HT 7) …
Central 5-HT4 receptors
RM Eglen, EHF Wong, A Dumuis, J Bockaert - Trends in Pharmacological …, 1995 - cell.com
Activation of the 5-HT 4 receptor mediates widespread effects in central and peripheral
nervous systems. Recent developments, such as the identification of novel, selective …
nervous systems. Recent developments, such as the identification of novel, selective …
Serotonin 5-HT7 receptor agents: structure-activity relationships and potential therapeutic applications in central nervous system disorders
M Leopoldo, E Lacivita, F Berardi, R Perrone… - Pharmacology & …, 2011 - Elsevier
Since its discovery in the 1940s in serum, the mammalian intestinal mucosa, and in the
central nervous system, serotonin (5-HT) has been shown to be involved in virtually all …
central nervous system, serotonin (5-HT) has been shown to be involved in virtually all …
The serotonin 5-HT7 receptors: two decades of research
E Gellynck, K Heyninck, KW Andressen… - Experimental brain …, 2013 - Springer
Like most neurotransmitters, serotonin possesses a simple structure. However, the
pharmacological consequences are more complex and diverse. Serotonin is involved in …
pharmacological consequences are more complex and diverse. Serotonin is involved in …
Pharmacology and Therapeutic Potential of the 5-HT7 Receptor
KM Blattner, DJ Canney, DA Pippin… - ACS Chemical …, 2018 - ACS Publications
It is well-documented that serotonin (5-HT) exerts its pharmacological effects through a
series of 5-HT receptors. The most recently identified member of this family, 5-HT7, was first …
series of 5-HT receptors. The most recently identified member of this family, 5-HT7, was first …
Serotonin receptors of type 6 (5-HT6): what can we expect from them?
D Marazziti, S Baroni… - Current medicinal …, 2011 - ingentaconnect.com
The serotonin (5-HT) receptors of type 6 (5-HT6) are relatively new. They are quite different
from all other 5-HT receptors, as they are characterized by a short third cytoplasmatic loop …
from all other 5-HT receptors, as they are characterized by a short third cytoplasmatic loop …
5-HT7 Receptors as Favorable Pharmacological Targets for Drug Discovery
PB Hedlund, JG Sutcliffe - The serotonin receptors: from molecular …, 2006 - Springer
Abstract The 5-hydroxytryptamine 7 (5-HT 7) receptor was among a group of 5-HT receptors
discovered through targeted cloning strategies 13 yr ago. It is a seven-transmembrane …
discovered through targeted cloning strategies 13 yr ago. It is a seven-transmembrane …
5-HT4 Receptors: Potential Therapeutic Implications in Neurology and Psychiatry
Serotonin 5-HT 4 receptors were first described in mouse colliculi neurons. They are
positively coupled to adenylyl cyclase, and possess unique pharmacological properties …
positively coupled to adenylyl cyclase, and possess unique pharmacological properties …
The 5-HT1A receptor: an overview of recent advances
SE Mestikawy, A Fargin, JR Raymond, H Gozlan… - Neurochemical …, 1991 - Springer
Progress in the field of neuronal receptor research has accelerated during the last few years
due to developments in pharmacology and molecular biology. This is particularly true in the …
due to developments in pharmacology and molecular biology. This is particularly true in the …
Serotonin 5-HT3 receptors in the central nervous system
P Chameau, JA van Hooft - Cell and tissue research, 2006 - Springer
The 5-HT 3 receptor is a ligand-gated ion channel activated by serotonin (5-HT). Although
originally identified in the peripheral nervous system, the 5-HT 3 receptor is also …
originally identified in the peripheral nervous system, the 5-HT 3 receptor is also …